… In conclusion, we found higher rates of BRAF V600E mutation over a 15-… mutations in
papillary thyroid cancer thus may contribute to the increasing incidence of papillary thyroid cancer. …

… cancers. The aim of the present study was to determine the frequency of BRAF mutations in
thyroid cancer … six human thyroid cancer cell lines and 207 paraffin-embedded thyroid tumor …

… BRAF mutations may be an important event in the development of papillary thyroid cancer. …
Our observation of a high frequency of BRAF-activating mutations in papillary thyroid …

… thyroid cancers are classified into papillary thyroid cancer (PTC), follicular thyroid cancer (FTC),
and anaplastic thyroid cancer (ATC)… for 85–90% of all thyroid malignancies.Differentiated …

… exon 15 mutations in papillary thyroid carcinomas. M, SKMel 28 melanoma line, Positive
control (BRAFV599E); L, normal subject blood lymphocytes; NPA, papillary carcinoma cell line. …

… a large series of 208 papillary thyroid cancers (PTC) followed … genetic alterations, including
point mutations and fusions. … V600E and TERT promoter mutations being the most frequent …

… mutation was higher in conventional papillary thyroid cancer (… papillary thyroid cancer (24.1%)
and follicular thyroid cancer (… conventional papillary thyroid cancer, BRAF V600E mutation …

… Almost one-third of human tumours are presented with RAS mutations 48 . Mutations of
RAS were initially reported in thyroid cancer in 1988 66 . They are found in a wide variety of …

… genes and signal pathways during progression of papillary thyroid cancer (PTC) via next-…
Direct Sanger sequencing was applied to validate the identified mutations. Results: Among …

… ) with papillary thyroid cancer (PTC), and different mutations … However, BRAF mutations have
not been adequately studied … None of our PTC (0/10) contained ras mutations, but 7/12 (58…