… BRAF mutation represents the most common oncogenic event in sporadic papillary thyroid
cancer (PTC). There are, however, significant discrepancies regarding the overall frequency …

… In summary, the available data provide evidence that in papillary thyroid cancer, distinct
mutational mechanisms are linked to specific environmental factors that have a role in …

… PAPILLARY THYROID CARCINOMA (PTC) is the most frequent of the histological subtypes
of thyroid cancers. … Because mutation of BRAF plays an important role in tumorigenesis and …

… Kaplan-Meier survival curves of effect of BRAF V600E mutation status on disease
recurrence–free probability in patients with various types of papillary thyroid cancer (PTC) …

… mutation has been shown to be associated with aggressive clinicopathologic characteristics
of papillary thyroid cancer … relationship of the BRAF mutation with clinicopathologic factors in …

… Putative cancer driver mutations have been identified in more than 98% of PTC, and a new
PTC classification into molecular subtypes has been proposed in order to resolve clinical …

… To discover driver mutations in thyroid cancers, we applied additional filtration criteria to
variant calls, as follows: 1) not or rarely shown in public databases of normal individuals, such …

… : The BRAF V600E mutation is closely related to serum Tg elevation after treatment with
iodine-131 in papillary thyroid cancer. These findings suggest that this BRAF mutation may be a …

… the BRAFV600E mutation, resulting in poor clinical outcomes of papillary thyroid carcinoma,
… with aggressive clinical behaviors of papillary thyroid microcarcinoma (PTMC) has not been …

… of CHEK2 mutations with thyroid cancer, we genotyped 468 unselected patients with
papillary thyroid cancer and 468 (matched) cancer-free controls for four founder mutations of …