Papillary thyroid cancer: pathological parameters as prognostic factors in different classes of age
P Miccoli, MN Minuto, C Ugolini… - … –Head and Neck …, 2008 - journals.sagepub.com
P Miccoli, MN Minuto, C Ugolini, E Panicucci, M Massi, P Berti, F Basolo
Otolaryngology–Head and Neck Surgery, 2008•journals.sagepub.comOBJECTIVE: To analyze aspects of a series of papillary thyroid carcinomas and evaluate the
prognostic features specific to different age classes. STUDY DESIGN: Retrospective study.
SUBJECTS AND METHODS: From 2000 to 2005, 2709 patients underwent a total
thyroidectomy for papillary thyroid carcinoma in our department. Patients were divided into
three groups:< 18 years (G1), 19 to 45 years (G2), and> 46 years (G3). Histologic and
clinical features were statistically evaluated. RESULTS: Tumor size was larger in G1 when …
prognostic features specific to different age classes. STUDY DESIGN: Retrospective study.
SUBJECTS AND METHODS: From 2000 to 2005, 2709 patients underwent a total
thyroidectomy for papillary thyroid carcinoma in our department. Patients were divided into
three groups:< 18 years (G1), 19 to 45 years (G2), and> 46 years (G3). Histologic and
clinical features were statistically evaluated. RESULTS: Tumor size was larger in G1 when …
OBJECTIVE: To analyze aspects of a series of papillary thyroid carcinomas and evaluate the prognostic features specific to different age classes.
STUDY DESIGN: Retrospective study.
SUBJECTS AND METHODS: From 2000 to 2005, 2709 patients underwent a total thyroidectomy for papillary thyroid carcinoma in our department. Patients were divided into three groups: <18 years (G1), 19 to 45 years (G2), and >46 years (G3). Histologic and clinical features were statistically evaluated.
RESULTS: Tumor size was larger in G1 when compared with both G2 and G3 (P < 0.0001). Infiltration of the thyroid capsule and node metastases were higher in G1 than both G2 and G3 (P < 0.0001). The Tall-cell variant was more represented in G2 and G3.
CONCLUSION: In the pediatric population, papillary carcinoma is a more aggressive disease. Because pediatric cancers have a better prognosis than their adult counterparts, this does not influence patient outcome. Age can then be considered the most important factor in determining prognosis.
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