Papillary thyroid carcinoma behavior: clues in the tumor microenvironment

K Bergdorf, DC Ferguson, M Mehrad… - … -Related Cancer, 2019 - erc.bioscientifica.com
… primary tumor fails to predict the likelihood of metastatic or recurrent disease. We predict
that the thyroid tumor immune microenvironment may play an important role in tumor behavior …

[HTML][HTML] Immune cell confrontation in the papillary thyroid carcinoma microenvironment

Z Xie, X Li, Y He, S Wu, S Wang, J Sun, Y He… - Frontiers in …, 2020 - frontiersin.org
… , and systematic research on the PTC immune microenvironment remains to be conducted.
… the PTC microenvironment and to summarize the changes in the immune microenvironment

Impact of the tumor microenvironment on the gene expression profile in papillary thyroid cancer

M Oczko-Wojciechowska, A Pfeifer, M Jarzab… - Pathobiology, 2020 - karger.com
tumor cells and microenvironment, in the present study, we compared the gene expression
profiles of PTC and normal thyroid in … the complexity of tumor-microenvironment crosstalk and …

[HTML][HTML] A distinct tumor microenvironment makes anaplastic thyroid cancer more lethal but immunotherapy sensitive than papillary thyroid cancer

PZ Han, WD Ye, PC Yu, LC Tan, X Shi, XF Chen, C He… - JCI insight, 2024 - ncbi.nlm.nih.gov
… Key differences in the tumor microenvironments of anaplastic thyroid cancer and papillary
thyroid cancer may underlie the disparity in prognosis and sensitivity to immunotherapy …

[HTML][HTML] Tumor mutation burden predicts relapse in papillary thyroid carcinoma with changes in genes and immune microenvironment

M Guo, Z Chen, Y Li, S Li, F Shen, X Gan… - Frontiers in …, 2021 - frontiersin.org
… Background: The risk factors of papillary thyroid carcinoma (PTC) recurrence are … Papillary
thyroid carcinoma (PTC) is the most common pathological type of thyroid carcinoma, with a …

TREM1 fosters an immunosuppressive tumor microenvironment in papillary thyroid cancer

Y Zhao, C Zhang, Y Zhu, X Ding… - … -Related Cancer, 2022 - erc.bioscientifica.com
… The immunosuppressive microenvironment is associated with poor prognosis in papillary
thyroid cancer (PTC); however, the molecular mechanisms involved are unknown. Among the …

[HTML][HTML] Mechanisms of the impact of hashimoto thyroiditis on papillary thyroid carcinoma progression: relationship with the tumor immune microenvironment

O Sulaieva, O Chernenko, O Selesnov… - Endocrinology and …, 2020 - ncbi.nlm.nih.gov
… The relationship between Hashimoto thyroiditis (HT) and papillary thyroid carcinoma (PTC)
remains uncertain. We assessed the impact of HT on the tumor immune microenvironment (…

[HTML][HTML] The thyroid tumor microenvironment: potential targets for therapeutic intervention and prognostication

L MacDonald, J Jenkins, G Purvis, J Lee… - Hormones and Cancer, 2020 - Springer
… that drive tumor initiation and progression [9]. Here, we will review stromal cells and
components of the tumor microenvironment in thyroid cancer that contribute to thyroid cancer

Tumor immune microenvironment characteristics of papillary thyroid carcinoma are associated with histopathological aggressiveness and BRAF mutation status

C Means, DR Clayburgh, L Maloney, D Sauer… - Head & …, 2019 - Wiley Online Library
… immune microenvironments, and revealed that tumors with aggressive pathological features
exhibit a predominantly myeloid TiME composition as compared to nonaggressive tumors

Tumor Microenvironment–Associated Pericyte Populations May Impact Therapeutic Response in Thyroid Cancer

A Iesato, C Nucera - Tumor Microenvironment: Novel Concepts, 2021 - Springer
tumor microenvironment may include inflammatory cells, and thyroid cancer microenvironment
consists of immune cells, endothelial cells, pericytes, cancer-associated fibroblasts (CAFs…