Paracoccidioides species present distinct fungal adherence to epithelial lung cells and promote different IL-8 secretion levels

BR Almeida, BCSC Barros, ACL Araújo… - Medical Microbiology …, 2020 - Springer
… to different isolates or species of the genus Paracoccidioides [20, 21], in the present work,
we compared IL-8 levels secreted by A549 lung epithelial cells when infected with isolates …

[HTML][HTML] Paracoccidioides brasiliensis induces secretion of IL-6 and IL-8 by lung epithelial cells. Modulation of host cytokine levels by fungal proteases

PK Maza, P Oliveira, MS Toledo, DMB Paula… - Microbes and …, 2012 - Elsevier
… depends on different MAPK pathways that are activated according to epithelial cell type and
pathogen species, reflecting, in this manner, the interaction between distinct host receptors …

The Trojan Horse Model in Paracoccidioides: A Fantastic Pathway to Survive Infecting Human Cells

G Giusiano - Frontiers in cellular and infection microbiology, 2021 - frontiersin.org
… The etiological agents are thermally dimorphic species of the genus Paracoccidioides. Infection
occurs via respiratoryLung cells such as DCs are part of the first line of defense against …

Alginate-Based 3D A549 Cell Culture Model to Study Paracoccidioides Infection

KS Dos Santos, LT Oliveira, M de Lima Fontes… - Journal of Fungi, 2023 - mdpi.com
… the interactions between Paracoccidioides brasiliensis (Pb) and lung epithelial cells. The …
for causing paracoccidioidomycosis (PCM), and P. brasiliensis is a common species, which, …

New insights into a complex fungal pathogen: the case of Paracoccidioides spp.

A Gonzalez, O Hernandez - Yeast, 2016 - Wiley Online Library
… In addition, pulmonary cells (mainly macrophages) are activated and an inflammatory …
performed using Paracoccidioides yeast cells after exposition to reactive nitrogen species (RNS) …

The pathobiology of Paracoccidioides brasiliensis

MI Borges-Walmsley, D Chen, X Shu… - Trends in microbiology, 2002 - cell.com
… Adult paracoccidioidomycosis primarily afflicts the lungs, leading to significant morbidity
due to gross impairment of lung function. Subsequently, the disease can disseminate to other …

[HTML][HTML] THE POWER OF THE SMALL: THE EXAMPLE OF Paracoccidioides brasiliensis CONIDIA

A Restrepo, LE Cano, A Gonzalez - Revista do Instituto de Medicina …, 2015 - SciELO Brasil
… Thus C were shown to be capable of producing active disease in healthy animals. Under …
of Paracoccidioides brasiliensis conidia to epithelial lung cells. Med Mycol. 2012;50:533-7.. …

… patterns of yeast cell morphology and host responses induced by representative strains of Paracoccidioides brasiliensis (Pb18) and Paracoccidioides lutzii (Pb01)

IM Siqueira, CLF Fraga, AC Amaral, ACO Souza… - …, 2015 - academic.oup.com
… The inflammatory reaction in the lung tissue in response to P… Paracoccidioides species
differentially induced the production of all cytokines/chemokines analyzed in either dendritic cells

[HTML][HTML] Expression of adhesion molecules in lungs of mice infected with Paracoccidioides brasiliensis conidia

A Gonzalez, HL Lenzi, EM Motta, L Caputo… - Microbes and …, 2005 - Elsevier
… ) in lungs of BALB/c mice infected with Paracoccidioides brasiliensis conidia. When compared
with uninfected animals, … The lung tissue homogenate was then serially diluted in PBS and …

[HTML][HTML] Fibrotic sequelae in pulmonary paracoccidioidomycosis: histopathological aspects in BALB/c mice infected with viable and non-viable Paracoccidioides …

AM Cock, LE Cano, D Velez, BH Aristizábal… - Revista do Instituto de …, 2000 - SciELO Brasil
… In a more recent study with this model, the sustained increase in lung tissue levels of TNF-a …
-infected mice and animals inoculated with fragmented yeast cells, revealed two important …