The paradox of autophagy and its implication in cancer etiology and therapy
A Eisenberg-Lerner, A Kimchi - Apoptosis, 2009 - Springer
… autophagy and cancer is complex. This review will discuss the link … autophagy and
cancer and will explore different autophagy-inducing drugs that are being used as anti-cancer …
cancer and will explore different autophagy-inducing drugs that are being used as anti-cancer …
Crosstalk between ROS and autophagy in tumorigenesis: understanding the multifaceted paradox
… Moreover, autophagy also plays a dual role, initially inhibiting tumor formation but … autophagy
and ROS where they can either suppress cancer formation or promote disease etiology. …
and ROS where they can either suppress cancer formation or promote disease etiology. …
Dual role of autophagy in hallmarks of cancer
… autophagy, mechanism of autophagy, as well as the paradoxical role of autophagy in cancer.
… elaborate on how autophagy plays a role in several hallmarks of cancer, and emergence of …
… elaborate on how autophagy plays a role in several hallmarks of cancer, and emergence of …
Telomeres and cancer: resolving the paradox
J Nassour, TT Schmidt… - Annual review of cancer …, 2021 - annualreviews.org
… This review focuses on the current knowledge of the dual role of telomeres in cancer and …
etiology. … It is worthy to note, however, that the role of autophagy in cancer is dynamic and …
etiology. … It is worthy to note, however, that the role of autophagy in cancer is dynamic and …
The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death
RA González-Polo, P Boya, AL Pauleau… - Journal of cell …, 2005 - journals.biologists.com
… and the massive accumulation of autophagic vacuoles in various tissues (Eskelinen et al.,
2002; Tanaka et al., 2000). Loss of LAMP2 is also at the etiology of Danon disease, an X-…
2002; Tanaka et al., 2000). Loss of LAMP2 is also at the etiology of Danon disease, an X-…
Autophagy: cancer's friend or foe?
… autophagy as a homeostatic and regulatory mechanism is underscored by the association
of autophagy defects in the etiology … -promoting drugs may involve unwanted paradoxical …
of autophagy defects in the etiology … -promoting drugs may involve unwanted paradoxical …
The roles, controversies, and combination therapies of autophagy in lung cancer
Z Wang, C Zhou, S Yang - Cell Biology International, 2022 - Wiley Online Library
… exact function of autophagy in lung cancer are contradictory, … on lung cancer is that targeting
autophagy combined with … paradoxical reports about the exact function of autophagy in …
autophagy combined with … paradoxical reports about the exact function of autophagy in …
Molecular pathways: autophagy in cancer—a matter of timing and context
M Cicchini, V Karantza, B Xia - Clinical cancer research, 2015 - AACR
… in the etiology and/or … autophagy in cancer is complex and varies depending on the timing
and context of tumor development. Yet, despite the seemingly paradoxical roles of autophagy …
and context of tumor development. Yet, despite the seemingly paradoxical roles of autophagy …
The multifaceted roles of autophagy in tumors—implications for breast cancer
J Debnath - Journal of mammary gland biology and neoplasia, 2011 - Springer
… and suppressive functions for autophagy, these paradoxical effects are reconciled through
a model in which the exact role of autophagy during cancer progression depends on tumor …
a model in which the exact role of autophagy during cancer progression depends on tumor …
Therapeutic modulation of autophagy: which disease comes first?
MC Maiuri, G Kroemer - Cell Death & Differentiation, 2019 - nature.com
… On a pessimistic note, it is possible that close-to-etiological treatments like autophagy
induction would be administered at a stage that is too late to arrest—let alone, to revert—the …
induction would be administered at a stage that is too late to arrest—let alone, to revert—the …
相关搜索
- cancer etiology and therapy
- autophagy in cancer development
- pro-tumor activity autophagy in cancer
- oxygen species regulation autophagy in cancer
- autophagy in cancer cells
- timing and context autophagy in cancer
- dynamic nature autophagy in cancer
- therapeutic implications autophagy in cancer
- multifaceted roles autophagy in cancer
- multifaceted paradox autophagy in tumorigenesis
- autophagy in lung cancer
- autophagy in breast cancer
- autophagy modulation in cancer
- autophagy in non-small cell lung cancer
- pro-survival autophagy hallmarks of cancer
- breast cancer development role of autophagy