… cancer. In this review, we summarize current knowledge on the regulation and dual function
… autophagy in tumorigenesis, as well as ongoing efforts in modulating autophagy for cancer …

… is considered as a double-edged sword in oncology, making anti-cancer therapeutic …
on autophagy regulation can help to develop new strategies and efficiently select novel anti-cancer …

… Therefore, understanding its etiology and … autophagic machinery; furthermore, reduced
autophagic activity is associated with aging while evidence suggests that enhanced autophagy …

… paradoxical result is due to the alleviation of age-associated dysfunctional autophagy which
… way that mirrors the etiology of human disease with regards to autophagic activity and aging…

… A complex multifactorial etiology of CRC is known, and, in recent years, autophagy has
been … Despite the seemingly paradoxical and dual role of autophagy in the context of tumor …

… Autophagy is a mechanism of protection against various forms of … as cancer, in which
autophagy seems to have an extremely complex role. In cancer, there is evidence that autophagy …

… Importantly, autophagy has often been described as a “double-edged sword” that can either
… cancer initiation and progression. Here, we overview such a dual function of autophagy in …

… complex paradoxical role of autophagy in cancer development as well as in cancer therapy.
… showing the involvement of autophagy in the pathology of HCC etiologic factors, mainly HBV…

… Autophagy has complex and paradoxical roles in … autophagy and cancer: it was found that
(1) the BECN1 gene is monoallelically deleted in several types of cancers, and (2) autophagy …

… autophagy is to be interpreted in the context of cancer. As outlined above, the unsolved
paradox is … (2009) The paradox of autophagy and its implication in cancer etiology and therapy. …