[HTML][HTML] Tumor Microenvironment Autophagic Processes and Cachexia: The Missing Link?
… The etiology of cancer cachexia in different tumor types involves complex and specific tumor…
are partly sustained by the paradoxical effect of autophagy in the tumor microenvironment. …
are partly sustained by the paradoxical effect of autophagy in the tumor microenvironment. …
[HTML][HTML] Recent advances in cellular signaling interplay between redox metabolism and autophagy modulation in cancer: an overview of molecular mechanisms and …
… to aid redox metabolism and autophagy modulation in cancer. Therefore, much work
remains before etiology or treatment concerns can be solved to enable redox-metabolism-mediated …
remains before etiology or treatment concerns can be solved to enable redox-metabolism-mediated …
Autophagy, Stem Cells, and Tumor Dormancy
DA Gewirtz - Autophagy: cancer, other pathologies, inflammation …, 2014 - Elsevier
… Autophagy … marked by recognition of the multiple roles of autophagy in various elements
of cancer development and treatment. During the course of autophagy (literally, self-eating), the …
of cancer development and treatment. During the course of autophagy (literally, self-eating), the …
The mystery of cancer resistance: A revelation within nature
… Role of genetic etiology in cancer in multiple species can be … The Peto’s paradox and G-value
paradox are evident when … the ROS levels through forming autophagosomes to get rid of …
paradox are evident when … the ROS levels through forming autophagosomes to get rid of …
Molecular pathways: old drugs define new pathways: non-histone acetylation at the crossroads of the DNA damage response and autophagy
OA Botrugno, T Robert, F Vanoli, M Foiani… - Clinical Cancer …, 2012 - AACR
… These data and the indication that autophagy is an … autophagy to improve cancer treatment,
particularly in apoptosis-defective contexts (38). Several clinical trials modulating autophagy …
particularly in apoptosis-defective contexts (38). Several clinical trials modulating autophagy …
[HTML][HTML] Autophagy as a modulator of cell death machinery
M Noguchi, N Hirata, T Tanaka, F Suizu… - Cell death & …, 2020 - nature.com
… Whether autophagy functions primarily in cell survival or cell … during autophagy and their
underlying mechanisms in cancer … that autophagy has an important role in the genetic etiology …
underlying mechanisms in cancer … that autophagy has an important role in the genetic etiology …
[HTML][HTML] Optimization of BCG therapy targeting neutrophil extracellular traps, autophagy, and miRNAs in bladder cancer: implications for personalized medicine
C Mao, X Xu, Y Ding, N Xu - Frontiers in medicine, 2021 - frontiersin.org
… Recently, the paradoxical role of autophagy in cancer … induce cell apoptosis and autophagy
in gastric cancer cells (114). … of autophagy in various cancers. BCG therapy is able to induce …
in gastric cancer cells (114). … of autophagy in various cancers. BCG therapy is able to induce …
Sarcoidosis and the mTOR, Rac1, and autophagy triad
Y Pacheco, CX Lim, T Weichhart, D Valeyre… - Trends in …, 2020 - cell.com
… to underlie sarcoidosis in humans, its etiology has been related to microbial, environmental,
… Specifically, we propose that dysfunction of mTOR, Rac1, and autophagy-related pathways …
… Specifically, we propose that dysfunction of mTOR, Rac1, and autophagy-related pathways …
The role of Autophagy in Hepatocellular Carcinoma
… and it is caused by different etiological factors: HBV and HCV … autophagy in both prevention
and promotion of liver cancer … autophagy, its dual role and its therapeutic potential in HCC. …
and promotion of liver cancer … autophagy, its dual role and its therapeutic potential in HCC. …
Regulation of mammalian autophagy in physiology and pathophysiology
… diseases, cancers, and Crohn's disease, we discuss the roles of autophagy in health and
disease, while trying to critically evaluate if the coincidence between autophagy and these …
disease, while trying to critically evaluate if the coincidence between autophagy and these …