Fluctuations in the symptoms of Parkinson's disease (PD), such as wearing‐off and on–off
effects, and dyskinesias are related to a variety of factors, including duration and dosage of …

… clinical characteristics, motor fluctuations, ie dyskinesia, dystonia, motor blocks and details
… had at least one type of motor fluctuation. Twenty three patients had motor blocks, 20 had …

… a disease duration of ≤5 years or ≥10 years. We conclude that motor fluctuations are most
strongly related to disease … rate of motor complications in patients with Parkinson's disease. …

… of motor fluctuations and dyskinesias. The risk of developing motor fluctuations has been linked
to disease … induces the development of motor fluctuations and dyskinesias and raises the …

… determining fluctuations in … fluctuating response to LD lends itself to a possible pharmacological
manipulation of the dopaminergic response to reverse, or even avoid, motor fluctuations (…

… was significantly shorter in patients with fluctuations of the on-off … Motor fluctuation severity
correlated best with initial efficacy decay slope, and both were best predicted by parkinsonian …

… Parkinsonian patients receiving long-term levodopa therapy generally develop fluctuations
… appears that a clinical continuum of motor fluctuations exists beginning with the wearingoff …

… are not only important to patients who experience fluctuations; the threat of motor fluctuations
dictates how patients are treated in early stages of the disease. Finally, motor fluctuations …

… of motor fluctuations, these fluctuations will ultimately occur in most patients, adding to the
disability in advanced stages of the illness. Treatment options for motor fluctuations include …

… Only a few years after the introduction of levodopa, the first descriptions of motor fluctuations
… develop fluctuations after chronic exposure to l-dopa. The diversity of fluctuating nonmotor …