Limitations of current Parkinson's disease therapy

O Rascol, P Payoux, F Ory, JJ Ferreira… - Annals of Neurology …, 2003 - Wiley Online Library
… interest in Parkinson's disease recently produced an evidence-based review of the efficacy,
safety, and usefulness of each of the current antiparkinsonian therapeutic interventions.2, 58 …

[HTML][HTML] Focusing brain therapeutic interventions in space and time for Parkinson's disease

S Little, P Brown - Current Biology, 2014 - cell.com
Parkinson’s disease, there are a number of promising emerging treatments. Here, we will
highlight three ambitious novel therapeuticParkinson's disease suggest host-to-graft disease

Neuroinflammatory mechanisms in Parkinson's disease: potential environmental triggers, pathways, and targets for early therapeutic intervention

MG Tansey, MK McCoy, TC Frank-Cannon - Experimental neurology, 2007 - Elsevier
… of Parkinson's disease (PD). Given that interplay between genetics and environment are
likely to contribute to risk for development of idiopathic PD, recent data showing interactions …

Treatment interventions for Parkinson's disease: an evidence based assessment

O Rascol, C Goetz, W Koller, W Poewe, C Sampaio - The Lancet, 2002 - thelancet.com
… Briefly, we reviewed the different therapeutic interventions … an established diagnosis of
Parkinson's disease, used objective … There are three types of therapeutic interventions considered …

Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention

MG Tansey, MS Goldberg - Neurobiology of disease, 2010 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease, after
Alzheimer's disease. The potential causes of PD remain uncertain, but recent studies suggest …

[HTML][HTML] Music therapy interventions in Parkinson's disease: the state-of-the-art

A Raglio - Frontiers in neurology, 2015 - frontiersin.org
Parkinson’s disease (PD) is a neurological disorder involving the progressive degeneration
of the dopaminergic system, which gives rise to movement-related dysfunctions (such as …

Therapies for Parkinson's diseases: alternatives to current pharmacological interventions

S Li, J Dong, C Cheng, W Le - Journal of neural transmission, 2016 - Springer
… light, gene therapy and cell replacement therapy, have also been suggested to give benefits
to relieve parkinsonian symptoms. This review will summarize and update the therapeutic

Parkinson's disease

B Thomas, MF Beal - Human molecular genetics, 2007 - academic.oup.com
… pathogenesis and identified probable targets for therapeutic intervention. Recent findings
implicate mitochondrial dysfunction, oxidative damage, abnormal protein accumulation and …

[HTML][HTML] Signaling pathways in Parkinson's disease: molecular mechanisms and therapeutic interventions

X Dong-Chen, C Yong, X Yang, ST Chen-Yu… - … and targeted therapy, 2023 - nature.com
… Most conventional therapeutic interventions for PD possess limited effects and have serious
side effects, heightening the need to develop novel treatments for this disease. In this review…

Alzheimer's and Parkinson's disease therapies in the clinic

P Chopade, N Chopade, Z Zhao… - Bioengineering & …, 2023 - Wiley Online Library
… of clinical intersections in therapeutic intervention strategies and a brief discussion of novel
preclinical strategies for these two most prevalent neurodegenerative diseases. This analysis …