Significant roles of neuroinflammation in Parkinson's disease: therapeutic targets for PD prevention
Glial cells outnumber neurons in the brain and play important roles in the neuroinflammation
that accompanies brain damage in neurodegenerative diseases. In Parkinson’s disease (…
that accompanies brain damage in neurodegenerative diseases. In Parkinson’s disease (…
Nrf2/ARE pathway as a therapeutic target for the treatment of Parkinson diseases
Instead of the progress in the understanding of etiology of Parkinson’s disease (PD), effective
methods to prevent the progression of the disease have not been developed and only …
methods to prevent the progression of the disease have not been developed and only …
Chaperone-mediated autophagy as a therapeutic target for Parkinson disease
P Campbell, H Morris, A Schapira - … opinion on therapeutic targets, 2018 - Taylor & Francis
Introduction: Parkinson disease (PD) is the most common neurodegenerative movement
disorder. Currently only symptomatic treatments exist for PD, and so the search for potential …
disorder. Currently only symptomatic treatments exist for PD, and so the search for potential …
Neuroinflammatory responses and Parkinson'disease: pathogenic mechanisms and therapeutic targets
L Yang, K Mao, H Yu, J Chen - Journal of Neuroimmune Pharmacology, 2020 - Springer
… More importantly, this review also emphasizes the potentially new therapeutic targets of … ,
the inflammasome is emerging as a potential therapeutic target. The level of NLRP3 has been …
the inflammasome is emerging as a potential therapeutic target. The level of NLRP3 has been …
[HTML][HTML] Neuroinflammation in Parkinson's disease and its potential as therapeutic target
Q Wang, Y Liu, J Zhou - Translational neurodegeneration, 2015 - Springer
… targets for PD and even other neurodegenerative diseases. A … and help to establish effective
therapeutic strategies. In this review, … therapeutic interventions targeting neuroinflammation. …
therapeutic strategies. In this review, … therapeutic interventions targeting neuroinflammation. …
LAMP2A as a therapeutic target in Parkinson disease
Abnormal aggregation of SNCA/α-synuclein plays a crucial role in Parkinson disease (PD) …
, CMA, represents a viable therapeutic target for PD and other synucleinopathies where …
, CMA, represents a viable therapeutic target for PD and other synucleinopathies where …
PPAR: a therapeutic target in Parkinson's disease
RK Chaturvedi, MF Beal - Journal of neurochemistry, 2008 - Wiley Online Library
Parkinson’s disease (PD) is a progressive and chronic neurodegenerative disorder,
characterized by progressive loss of dopaminergic neurons in substantia nigra. The etiology and …
characterized by progressive loss of dopaminergic neurons in substantia nigra. The etiology and …
TFEB: Pathogenic role and therapeutic target in Parkinson disease
M Decressac, A Björklund - Autophagy, 2013 - Taylor & Francis
Parkinson disease (PD) is characterized by the progressive loss of nigral dopamine
neurons and the presence of accumulations containing the disease-causing protein SNCA/α-…
neurons and the presence of accumulations containing the disease-causing protein SNCA/α-…
[HTML][HTML] Mitochondria: a therapeutic target for Parkinson's disease?
Parkinson’s disease (PD) is one of the most common neurodegenerative disorders. The …
We also summarize mitochondria-targeting therapeutics in models of PD, proposing that …
We also summarize mitochondria-targeting therapeutics in models of PD, proposing that …
Potential therapeutic targets for Parkinson's disease
J Stoessl - Expert opinion on therapeutic targets, 2008 - Taylor & Francis
Background: Parkinson's disease is a common disorder that becomes more prevalent with
advanced age. The cardinal features are related to dopamine deficiency, arising from loss of …
advanced age. The cardinal features are related to dopamine deficiency, arising from loss of …
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