Pulmonary deposition of lactose carriers used in inhalation powders

M Karhu, J Kuikka, T Kauppinen, K Bergström… - International journal of …, 2000 - Elsevier
… In our study, we have also investigated fine particle fractions of budesonide inhalation
powders using the Andersen cascade impactor. Budesonide was mixed with the carrier systems …

Dry powder inhalation: past, present and future

AH de Boer, P Hagedoorn, M Hoppentocht… - Expert opinion on …, 2017 - Taylor & Francis
… Chiesi claims to achieve higher lung deposition with better penetration into the small
airways with such particles, compared to inhalation powders with a larger MMAD, due to lower …

The influence of formulation on emission, deaggregation and deposition of dry powders for inhalation

DL French, DA Edwards, RW Niven - Journal of Aerosol Science, 1996 - Elsevier
… Carrier particles (PEG 8000) improved total powder emission, but in many instances reduced
the percent of active powder inhaled compared to formulations consisting of active powder

Effect of particle size of dry powder mannitol on the lung deposition in healthy volunteers

W Glover, HK Chan, S Eberl, E Daviskas… - International journal of …, 2008 - Elsevier
particle size of a DPI to the in vivo lung deposition using SPECT and mannitol as the dry
powder with different particleInhalation of the different particle size powders by the subjects …

Formation of particles for dry powder inhalers

L Gradon, TR Sosnowski - Advanced Powder Technology, 2014 - Elsevier
… We analyze a particle depositionparticle transport, deposition and retention in the respiratory
system coupled with the efficiency of the powder aerosolization with a dry powder inhaler (…

In vitro evaluation of dry powder inhalers I: drug deposition of commonly used devices

H Steckel, BW Müller - international journal of pharmaceutics, 1997 - Elsevier
powder inhaler has a specific air flow resistance that limits flow under in vivo conditions, inhaler
… to determine the fine particle fraction of commonly used dry powder inhalers. The results …

Deposition of inhaled particles in the lungs

AF Tena, PC Clarà - Archivos de Bronconeumología (English Edition), 2012 - Elsevier
… of the powder into particles that enter into the inhaled … the powder container, which break
the powder agglomerations up into smaller-sized particles and separate the transport particles

In Vitro Tests for Aerosol Deposition II: IVIVCs for Different Dry Powder Inhalers in Normal Adults

R Delvadia, M Hindle, PW Longest… - Journal of aerosol …, 2013 - liebertpub.com
… application to inhaled particle depositionBull Math Biol198042461480. 6. Yeh HC, and
Schum GM: Models of human lung airways and their application to inhaled particle deposition. …

Dissolution testing of powders for inhalation: influence of particle deposition and modeling of dissolution profiles

S May, B Jensen, C Weiler, M Wolkenhauer… - Pharmaceutical …, 2014 - Springer
… modeling the dissolution profile of powders for inhalation and other influencing factors under
… thickness, particle shape, and particle size distribution, especially for particles between 10 …

Effect of powder inhaler design on drug deposition in the respiratory tract

M Vidgren, A Kärkkäinen, P Karjalainen… - International journal of …, 1988 - Elsevier
… lung deposition of the inhaled drug particles. Thus the design of the dry powder inhaler was
… both on the emptying of the capsules as well as on the redispersion of the powder mixture. …