Pulmonary deposition of lactose carriers used in inhalation powders
M Karhu, J Kuikka, T Kauppinen, K Bergström… - International journal of …, 2000 - Elsevier
… In our study, we have also investigated fine particle fractions of budesonide inhalation
powders using the Andersen cascade impactor. Budesonide was mixed with the carrier systems …
powders using the Andersen cascade impactor. Budesonide was mixed with the carrier systems …
Dry powder inhalation: past, present and future
AH de Boer, P Hagedoorn, M Hoppentocht… - Expert opinion on …, 2017 - Taylor & Francis
… Chiesi claims to achieve higher lung deposition with better penetration into the small
airways with such particles, compared to inhalation powders with a larger MMAD, due to lower …
airways with such particles, compared to inhalation powders with a larger MMAD, due to lower …
The influence of formulation on emission, deaggregation and deposition of dry powders for inhalation
DL French, DA Edwards, RW Niven - Journal of Aerosol Science, 1996 - Elsevier
… Carrier particles (PEG 8000) improved total powder emission, but in many instances reduced
the percent of active powder inhaled compared to formulations consisting of active powder …
the percent of active powder inhaled compared to formulations consisting of active powder …
Effect of particle size of dry powder mannitol on the lung deposition in healthy volunteers
… particle size of a DPI to the in vivo lung deposition using SPECT and mannitol as the dry
powder with different particle … Inhalation of the different particle size powders by the subjects …
powder with different particle … Inhalation of the different particle size powders by the subjects …
Formation of particles for dry powder inhalers
L Gradon, TR Sosnowski - Advanced Powder Technology, 2014 - Elsevier
… We analyze a particle deposition … particle transport, deposition and retention in the respiratory
system coupled with the efficiency of the powder aerosolization with a dry powder inhaler (…
system coupled with the efficiency of the powder aerosolization with a dry powder inhaler (…
In vitro evaluation of dry powder inhalers I: drug deposition of commonly used devices
H Steckel, BW Müller - international journal of pharmaceutics, 1997 - Elsevier
… powder inhaler has a specific air flow resistance that limits flow under in vivo conditions, inhaler
… to determine the fine particle fraction of commonly used dry powder inhalers. The results …
… to determine the fine particle fraction of commonly used dry powder inhalers. The results …
Deposition of inhaled particles in the lungs
AF Tena, PC Clarà - Archivos de Bronconeumología (English Edition), 2012 - Elsevier
… of the powder into particles that enter into the inhaled … the powder container, which break
the powder agglomerations up into smaller-sized particles and separate the transport particles …
the powder agglomerations up into smaller-sized particles and separate the transport particles …
In Vitro Tests for Aerosol Deposition II: IVIVCs for Different Dry Powder Inhalers in Normal Adults
… application to inhaled particle depositionBull Math Biol198042461480. 6. Yeh HC, and
Schum GM: Models of human lung airways and their application to inhaled particle deposition. …
Schum GM: Models of human lung airways and their application to inhaled particle deposition. …
Dissolution testing of powders for inhalation: influence of particle deposition and modeling of dissolution profiles
S May, B Jensen, C Weiler, M Wolkenhauer… - Pharmaceutical …, 2014 - Springer
… modeling the dissolution profile of powders for inhalation and other influencing factors under
… thickness, particle shape, and particle size distribution, especially for particles between 10 …
… thickness, particle shape, and particle size distribution, especially for particles between 10 …
Effect of powder inhaler design on drug deposition in the respiratory tract
M Vidgren, A Kärkkäinen, P Karjalainen… - International journal of …, 1988 - Elsevier
… lung deposition of the inhaled drug particles. Thus the design of the dry powder inhaler was
… both on the emptying of the capsules as well as on the redispersion of the powder mixture. …
… both on the emptying of the capsules as well as on the redispersion of the powder mixture. …
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