Particle-size analysis of pharmaceutical powders
LJ Beaubien, AJ Vanderwielen - Journal of Pharmaceutical Sciences, 1980 - Elsevier
… The present study is part of a continuing project to automate the particle-size analysis of
powdered drugs used for formulating suspensions, capsules, and tablets. Milled and micronized …
powdered drugs used for formulating suspensions, capsules, and tablets. Milled and micronized …
Micron‐size drug particles: common and novel micronization techniques
N Rasenack, BW Müller - Pharmaceutical development and …, 2004 - Taylor & Francis
… Drug powders containing micron‐size drug particles are … of the particle surface and powder
properties plays an important … the production of a drug in small particle size. The properties of …
properties plays an important … the production of a drug in small particle size. The properties of …
Influence of cohesive properties of micronized drug powders on particle size analysis
MM De Villiers - Journal of pharmaceutical and biomedical analysis, 1995 - Elsevier
… fine drug particles on particle size analysis. It was done by comparing the differences between
particle size … , chloramphenicol palmitate and acetaminophen particles in the same and in …
particle size … , chloramphenicol palmitate and acetaminophen particles in the same and in …
Combinative particle size reduction technologies for the production of drug nanocrystals
J Salazar, RH Müller… - Journal of …, 2014 - Wiley Online Library
… The freeze-dried drug powder was processed to a … bar producing drug nanocrystals of a 62
nm mean particle size [41]… particle size, as slowly freezing the drug solution resulted in bigger …
nm mean particle size [41]… particle size, as slowly freezing the drug solution resulted in bigger …
Particle size analysis in pharmaceutics: principles, methods and applications
BY Shekunov, P Chattopadhyay, HHY Tong… - Pharmaceutical …, 2007 - Springer
… distributions in a variety of products, such as metered dose inhaler and dry powder
inhaler drug products (67), and nasal spray and inhalation solution, suspension, and spray …
inhaler drug products (67), and nasal spray and inhalation solution, suspension, and spray …
Ranking in vitro dissolution of inhaled micronized drug powders including a candidate drug with two different particle sizes
… clinical development when drug particle size distribution (PSD) … drug substance (CDS)
present in two different particle size distributions (AZD5423 1.3 and AZD5423 3.1 ) as powders …
present in two different particle size distributions (AZD5423 1.3 and AZD5423 3.1 ) as powders …
Dissolution rates of finely divided drug powders I. Effect of a distribution of particle sizes in a diffusion‐controlled process
WI Higuchi, EN Hiestand - Journal of pharmaceutical sciences, 1963 - Wiley Online Library
… of time, particle size, a, is the only variable with time. From the volume of the particle, v,
and … In practice, many materials have particle size distributions that correspond to a relatively …
and … In practice, many materials have particle size distributions that correspond to a relatively …
The influence of particle size distribution and surface roughness of carrier particles on the in vitro properties of dry powder inhalations
F Podczeck - Aerosol Science & Technology, 1999 - Taylor & Francis
… of dry powder … dry powder inhalations, whereas carrier powders with comparatively rough
surfaces lose their ability to function as carrier particles for a micronized drug in a dry powder …
surfaces lose their ability to function as carrier particles for a micronized drug in a dry powder …
Adhesion forces in interactive powder mixtures of a micronized drug and carrier particles of various particle size distributions
F Podczeck - Journal of adhesion science and technology, 1998 - Taylor & Francis
… model drug and carrier powder, respectively. Furthermore, different particle size distribution
… was an optimal particle size distribution of carrier particles for dry powder inhalations. In a …
… was an optimal particle size distribution of carrier particles for dry powder inhalations. In a …
Miniaturization of powder dissolution measurement and estimation of particle size
A Avdeef, K Tsinman, O Tsinman, N Sun… - Chemistry & …, 2009 - Wiley Online Library
… estimating particle size from powder dissolution measurement using as little as 50 μg of
sample in 1 ml of buffer solutions. The powder dissolution profiles of five sparingly-soluble drugs …
sample in 1 ml of buffer solutions. The powder dissolution profiles of five sparingly-soluble drugs …
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