… immune response. As a starting point we will summarize the biological processes involved in
immune response development upon vaccination… requirements of particulate vaccines and …

… applications of particle-based immune adjuvants. Since the size of the particulate adjuvants
… of the size of particulate adjuvants on the resultant immune responses and offered a few …

… review the role of the size, shape and rigidity of particulate vaccines in enhancing and
skewing T cell response and attempted to provide a “roadmap” for rational vaccine design. …

… and the subsequent endo/phagosomal maturation and immune responses, and on how
this knowledge can be used in particle-based vaccine design. We therefore compared both …

… than hydrophilic particles. Furthermore, shape and composition of adjuvant particles also
influence on immune responses. This review gives an insight into the impact of particle size, …

… One can now envisage the design of tailored systems to specifically control the type of
adaptive immune responses elicited by vaccines in order to control cancers and infectious …

… In the present investigation, direct injection of particulate vaccines into the lymph nodes
provides the highest immuno-availability of antigen, which explains why this route was superior …

… were well tolerated and many of the volunteers who received aerosol vaccinations
exhibited … vaccination. A mucosal immune response was induced by aerosol vaccination as …

… for optimal immune responses, and we emphasized this through murine vaccination studies
… 1 and IgG 2a ), and IFN-γ responses than soluble Ag and CpG ODN.Citation 36 Improved …

… in immune response were observed by others (8,17). However, immune response produced
by negatively charged particles … than that produced by particles of similar charge used in our …