[HTML][HTML] Allergic Airway Inflammation by Nasal Inoculation of Particulate Matter (PM2.5) in NC/Nga Mice

K Ogino, R Zhang, H Takahashi, K Takemoto, M Kubo… - PloS one, 2014 - journals.plos.org
… Intracellular deposits of insoluble particulates were observed in macrophages around
inflammatorymechanism and synergistic action of insoluble particulates and soluble components. …

Pathogenic role of air pollution particulate matter in cardiometabolic disease: evidence from mice and humans

T Marchini, A Zirlik, D Wolf - Antioxidants & redox signaling, 2020 - liebertpub.com
Mechanisms of vascular inflammation and leukocyte recruitment after PM inhalation.
Cytokines locally secreted in the lung, mostly by alveolar macrophages, activate both, circulating …

The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles

N Li, T Xia, AE Nel - Free radical biology and medicine, 2008 - Elsevier
… exacerbation of inflammation, especially in susceptible people. One of the mechanisms by
which … In this communication, we will review the mechanisms by which particulate pollutants, …

[HTML][HTML] Particulate matter exposure is associated with inflammatory gene methylation in obese subjects

L Cantone, S Iodice, L Tarantini, B Albetti… - Environmental …, 2017 - Elsevier
… Our findings, taken together, may reflect the biological mechanism underlying the beginning
of the inflammatory cascade. CD14 could represent a key actor of the inflammatory pathway …

[HTML][HTML] A comprehensive understanding of ambient particulate matter and its components on the adverse health effects based from epidemiological and laboratory …

T Li, Y Yu, Z Sun, J Duan - Particle and fibre toxicology, 2022 - Springer
… Based on the AOP Wiki and the mechanisms of PM-induced toxicity at … inflammation by
activating inflammation-related pathways and increasing the secretion level of inflammatory

[HTML][HTML] Activation of the complement system on human endothelial cells by urban particulate matter triggers inflammation-related protein production

MS Choi, H Jeon, SM Yoo, MS Lee - International journal of molecular …, 2021 - mdpi.com
… Exposure to particulate matter (PM) is becoming a major … However, the mechanism through
which PM affects the vascular … mechanism of vascular inflammation elicited by air pollution. …

Urban particulate matter–activated human dendritic cells induce the expansion of potent inflammatory Th1, Th2, and Th17 effector cells

NC Matthews, PE Pfeffer, EH Mann… - American Journal of …, 2016 - atsjournals.org
… DCs with urban particulate matter alone induces resting … mechanism. Such responses might
contribute to the development and exacerbation of asthma. Asthma is a chronic inflammatory

[HTML][HTML] Particulate matter air pollution causes oxidant-mediated increase in gut permeability in mice

EA Mutlu, PA Engen, S Soberanes, D Urich… - Particle and fibre …, 2011 - Springer
particulate matter (PM) air pollution may be an important environmental factor leading to
exacerbations of inflammatory … junctions, apoptosis or other mechanisms are responsible for the …

[HTML][HTML] Molecular mechanisms underlying NLRP3 inflammasome activation and IL-1β production in air pollution fine particulate matter (PM2. 5)-primed macrophages

L Caceres, T Abogunloko, S Malchow, F Ehret… - Environmental …, 2024 - Elsevier
… Exposure to air pollution fine particulate matter (PM 2.5 ) aggravates respiratory and … local
inflammation that ignites a systemic response, but precise underlying mechanisms remain …

[HTML][HTML] Role of different mechanisms in pro-inflammatory responses triggered by traffic-derived particulate matter in human bronchiolar epithelial cells

M Refsnes, T Skuland, R Jørgensen… - Particle and Fibre …, 2023 - Springer
… to the adverse health effects of ambient particulate matter (PM). In … inflammatory responses
of mineral particles and DEP to PM from two road tunnels, and examined the mechanisms