Ambient particulate matter and respiratory and cardiovascular illness in adults: particle-borne transition metals and the heart–lung axis

RS Chapman, WP Watkinson, KL Dreher… - Environmental …, 1997 - Elsevier
… shown associations of exposure to ambient particulate matter (PM) with severe health effects,
… Rather, it should examine the entire heart–lung axis and should probably consider other …

Black tea alleviates particulate matter-induced lung injury via the gut-lung Axis in mice

Y Zhao, X Chen, J Shen, A Xu, Y Wang… - Journal of Agricultural …, 2021 - ACS Publications
… However, its impact on particulate matter (PM) induced lung … stress and inflammation in the
lungs, which was significantly alleviated … PM-induced lung injury via the gut-lung axis in mice. …

Research progress on the effects of gut microbiome on lung damage induced by particulate matter exposure

J Qin, J Wang - Environmental Research, 2023 - Elsevier
… damage and its possible interaction pathways and explores the potential immune inflammatory
mechanism with the gut-lung axis as the hub in order to understand the current research …

[HTML][HTML] Microglial priming through the lung–brain axis: The role of air pollution–induced circulating factors

CL Mumaw, S Levesque, C McGraw… - The FASEB …, 2016 - ncbi.nlm.nih.gov
… Mice were exposed 6 h/d for 50 d to either 300 μg particulate matter (PM)/m 3 , which was
a combination of roughly 50 μg PM/m 3 gasoline engine emissions mixed with 250 μg PM/m 3 …

[HTML][HTML] Every breath you take: Impacts of environmental dust exposure on intestinal barrier function–from the gut-lung axis to COVID-19

SC Meli'sa, TM Nordgren… - American Journal of …, 2021 - journals.physiology.org
Particulate matter induction of inflammation along the gut-lung axis. (1) When inhaled or
ingested dust can reach the alveolar space and promote immune responses. (2) …

Immune‐pineal axis protects rat lungs exposed to polluted air

CE Carvalho‐Sousa, EP Pereira… - Journal of pineal …, 2020 - Wiley Online Library
… the immune-pineal axis by switching the … axis under stressful conditions and provide
strong evidence that macrophage-synthesized melatonin retains particulate matter in the lung

[HTML][HTML] Instillation of particulate matter 2.5 induced acute lung injury and attenuated the injury recovery in ACE2 knockout mice

CI Lin, CH Tsai, YL Sun, WY Hsieh, YC Lin… - … journal of biological …, 2018 - ncbi.nlm.nih.gov
axis and angiotensin-converting enzyme II (ACE2)/angiotensin 1-7 (Ang-(1-7))/Mas receptor
(ACE2/Ang-(1-7)/Mas) axis … -7)/Mas axis has a crucial role in the pathogenesis of lung injury. …

Atmospheric fine particulate matter and epithelial mesenchymal transition in pulmonary cells: state of the art and critical review of the in vitro studies

M Cochard, F Ledoux, Y Landkocz - Journal of Toxicology and …, 2020 - Taylor & Francis
… Exposure to fine particulate matter (PM 2.5 ) has been associated with several diseases
including asthma, chronic obstructive pulmonary disease (COPD) and lung cancer. Mechanisms …

PP2A-mTOR-p70S6K/4E-BP1 axis regulates M1 polarization of pulmonary macrophages and promotes ambient particulate matter induced mouse lung injury

S Chen, L Chen, L Ye, Y Jiang, Q Li, H Zhang… - Journal of hazardous …, 2022 - Elsevier
To identify key signaling pathways involved in ambient particulate matter (PM)-induced
pulmonary injury, we generated a mouse model with myeloid-specific deletion of Ppp2r1a gene (…

Fine particulate matter constituents and stress hormones in the hypothalamus–pituitary–adrenal axis

Y Niu, R Chen, Y Xia, J Cai, Z Ying, Z Lin, C Liu… - Environment …, 2018 - Elsevier
… It may be plausible that only OC and EC with smaller sizes (eg <0.1 μm) has sufficient
capacity to translocating from lung to brain, and then to act on the HPA axis directly. …