Microtubule destabilization caused by particulate matter contributes to lung endothelial barrier dysfunction and inflammation

P Karki, A Meliton, A Sitikov, Y Tian, T Ohmura… - Cellular signalling, 2019 - Elsevier
… cardiovascular events of lung exposure to PM. However, the role of PM in acute lung injury
(… This study tested a hypothesis that PM augments lung injury and EC barrier dysfunction via …

[HTML][HTML] … particulate matter (PM2. 5)-induced lung injury by attenuation of ROS-mediated recruitment of neutrophils and Ly6Chigh monocytes and lung inflammation

CM Lin, TH Huang, MC Chi, SE Guo, CW Lee… - Ecotoxicology and …, 2022 - Elsevier
particulate matter (PM) may contribute to lung inflammation … (PM2.5)-induced lung injury is
poorly understood. This study … and Ly6C high monocytes into lung alveoli and the production …

[HTML][HTML] The NLRP3 inflammasome in pathogenic particle and fibre-associated lung inflammation and diseases

M Sayan, BT Mossman - Particle and fibre toxicology, 2015 - Springer
… maturation of pro-inflammatory chemokines and cytokines, … inflammation after inhalation of
pathogenic pollutants such as asbestos, crystalline silica (CS), and airborne particulate matter

Oxidative stress, DNA damage, and inflammation induced by ambient air and wood smoke particulate matter in human A549 and THP-1 cell lines

PH Danielsen, P Møller, KA Jensen… - Chemical research in …, 2011 - ACS Publications
… air and indoor levels of particulate matter (PM). Toxicological … toxicity end points in human
A549 lung epithelial and THP-1 … , DNA damage as well as inflammatory and oxidative stress …

Role of iron and oxidative stress in the exacerbation of allergic inflammation in murine lungs caused by urban particulate matter< 2.5 μm and desert dust

M He, T Ichinose, S Yoshida… - Journal of Applied …, 2019 - Wiley Online Library
lung eosinophilia (Ren et al., 2014). However, the contamination level of LPS (1 ng) did not
exacerbate OVA-induced allergic lung inflammation… in exacerbation of lung inflammation and …

Urban particulate matter activates Akt in human lung cells

TL Watterson, B Hamilton, RS Martin… - Archives of toxicology, 2012 - Springer
… pro-inflammatory, through a variety of mechanisms involving the release of inflammatory
cytokines… Human lung (BEAS-2B) cells were treated with either fine (PM 2.5 ) or coarse (PM 10 ) …

[HTML][HTML] Inhaled pollutants: the molecular scene behind respiratory and systemic diseases associated with ultrafine particulate matter

H Traboulsi, N Guerrina, M Iu, D Maysinger… - International journal of …, 2017 - mdpi.com
… contribute to alterations in inflammation. Additional studies using TiO 2 inhalation in mice
has revealed significant changes in lung inflammatory cells (predominantly increased …

Acute exposure to diesel-biodiesel particulate matter promotes murine lung oxidative stress by Nrf2/HO-1 and inflammation through the NF-kB/TNF-α pathways

I Cattani-Cavalieri, SS Valenca, M Lanzetti… - Inflammation, 2019 - Springer
… DB particulate matter penetrated the lung in the 250-μg and 1000-μg groups. In addition, the
DB particulate matter … exposure of murine lungs to DB particulate matter resulting from fuel …

[HTML][HTML] Recent Insights into Particulate Matter (PM2.5)-Mediated Toxicity in Humans: An Overview

P Thangavel, D Park, YC Lee - International journal of environmental …, 2022 - mdpi.com
… the lung and can navigate through bronchioles and escape lung … accumulates in the lungs
and activates inflammatory cells, … is inflammation in the lungs due to PM 2.5 , the inflammation

Lung antioxidant and cytokine responses to coarse and fine particulate matter from the great California wildfires of 2008

TC Wegesser, LM Franzi, FM Mitloehner… - Inhalation …, 2010 - Taylor & Francis
… Our results point to TNF-α as a significant cytokine involved in the mouse lung inflammatory
response to PM. Javala et al. (Citation2006) reported slightly decreased levels of TNF-α in …