… airway epithelial cells (HAECs) stand out as a particularly important and … cell type for study
for several reasons. Since they line the pulmonary epithelium, HAECs are typically the first cell …

… The human alveolar cell line A549 (ATTC, Rockville, MD, USA) was used as a model for
human lung epithelial type II cells. Cells were exposed to the concentration of 6 μg cm −2 of PM. …

… lung conditions, such as, chronic obstructive pulmonary … in the respiratory tract depends
predominantly on the size of … those elicited by PM exposure of lung cells are remarkably similar. …

… particulate matter (PM) from different sources. Long-term exposure to high levels of these
particulates has been linked to a diverse range of respiratory … properties, and size contribute to …

… airborne particulate matter (PM) as an important environmental pollutant for many
different cardiopulmonary diseases and lung … factors and induce apoptosis of lung cells (Citation106). …

… primary human bronchial epithelial cells (HBECs) exposed to … lung, cultured to confluence,
and exposed to 10 to 500 μ g/ml of a suspension of ambient particulate matter with a diameter …

… and decreases in cell viability were observed in this study for all three PM size fractions.
However, only the ultrafine particle data supported the differential cellular responses proposed …

… with particle size and by a season:size interaction, … size, locale (ie urban versus rural), and
site of PM samples affected the ROS response in pulmonary endothelial and epithelial cells …

… parenchyma we evaluated the levels of Caspase8-p18, involved in the programmed cell
death, of heme oxygenase-1 (HO-1), an enzyme induced by stimuli such as oxidative stress, …

… CB of an aerodynamic diameter similar to that of our filter extracted particles was consistently
less effective than the winter urban PM 2.5 here tested for inducing ROS production and …