Pathogenesis of acute kidney injury: foundation for clinical practice

GR Kinsey, MD Okusa - American Journal of Kidney Diseases, 2011 - Elsevier
… This review highlights several pathogenic mechanisms in AKI for … kidney and bone
marrow–derived cells and innate and adaptive immunity reflect the complexities in acute kidney injury

Pathogenesis of acute kidney injury in coronavirus disease 2019

JY Qian, B Wang, LL Lv, BC Liu - Frontiers in physiology, 2021 - frontiersin.org
… Although acute respiratory disorder is the main manifestation of COVID-19, acute kidney
injury (… This article reviews the current understanding of the pathogenesis of AKI in COVID-19. …

Role of leukocytes in the pathogenesis of acute kidney injury

GR Kinsey, MD Okusa - Critical care, 2012 - Springer
Acute kidney injury (AKI) is a significant cause of morbidity and mortality in hospitalized
patients, especially those who are critically ill. The mortality rate in patients with severe AKI …

Role of C‐reactive protein in the pathogenesis of acute kidney injury

Y Tang, SK Mak, AP Xu, HY Lan - Nephrology, 2018 - Wiley Online Library
… as an active participant in the pathogenesis and progression of AKI by exacerbating local …
fibrosis of injured renal tissue. Both the pathogenesis and prognosis of acute kidney injury (AKI…

MicroRNAs in pathogenesis of acute kidney injury

Z Liu, S Wang, QS Mi, Z Dong - Nephron, 2016 - karger.com
kidney diseases such as acute kidney injury (AKI). Recent studies have further implicated
specific miRNAs in the pathogenesis of … Further investigation will identify the key pathogenic

MicroRNA-21 in the pathogenesis of acute kidney injury

YF Li, Y Jing, J Hao, NC Frankfort, X Zhou… - Protein & …, 2013 - academic.oup.com
Acute kidney injury (AKI), associated with significant mor… response to ischemia or reperfusion
injury, which results in either … The innate immune response in ischemic acute kidney injury

Pathogenesis of acute kidney injury: effects of remote tissue damage on the kidney

X Wen, Z Peng, JA Kellum - Controversies in Acute Kidney Injury, 2011 - karger.com
… a variety of pathophysiological processes as kidney injury evolves. In this chapter, we will
discuss the pathogenesis of AKI in light of new information concerning injury and repair, and …

The pathogenesis of acute kidney injury and the toxic triangle of oxygen, reactive oxygen species and nitric oxide

U Aksu, C Demirci, C Ince - Controversies in Acute Kidney Injury, 2011 - karger.com
… Despite the advances made in the pathogenesis and treatment of acute kidney injury (AKI),
current therapeutic modalities have been ineffective for adequate treatment. Consequently, …

Pathogenesis of acute kidney injury during sepsis

Z Ricci, C Ronco - Current drug targets, 2009 - ingentaconnect.com
Acute kidney injury (AKI) is a complex disorder that occurs in a variety of settings with clinical
Acute kidney injury in the intensive care unit according to RIFLE. Crit Care Med 2007; 35: …

The role of tubuloglomerular feedback in the pathogenesis of acute kidney injury

P Singh, MD Okusa - Controversies in Acute Kidney Injury, 2011 - karger.com
… (GFR) in prerenal and intrarenal acute kidney injury (AKI) are not mutually exclusive and
prerenal mechanisms continue to play a role in the pathogenesis of established intrarenal AKI. …