Pathogenesis of idiopathic pulmonary fibrosis

PJ Wolters, HR Collard, KD Jones - Annual Review of Pathology …, 2014 - annualreviews.org
… to study molecular pathways of pulmonary fibrosis. However, pathologic … in idiopathic
pulmonary fibrosis. In the bleomycin model, the fibrosis evolves over months, whereas in idiopathic

The pathogenesis of idiopathic pulmonary fibrosis

WR Coward, G Saini, G Jenkins - Therapeutic advances in …, 2010 - journals.sagepub.com
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with an appalling
prognosis. The failure of anti-inflammatory therapies coupled with the observation that …

The role of infection in the pathogenesis of idiopathic pulmonary fibrosis

PL Molyneaux, TM Maher - European Respiratory Review, 2013 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a progressive, and invariably fatal, condition that is
believed to arise in genetically susceptible individuals as a consequence of an aberrant wound-…

[HTML][HTML] A new direction in the pathogenesis of idiopathic pulmonary fibrosis?

J Gauldie, M Kolb, PJ Sime - Respiratory research, 2001 - Springer
A recent review article suggested that idiopathic pulmonary fibrosis (IPF) is a disease that is
associated more with abnormal wound healing than with inflammation. Data derived from …

Pathogenesis of idiopathic pulmonary fibrosis and its clinical implications

P Spagnolo, G Rossi, A Cavazza - Expert review of clinical …, 2014 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is the most common and lethal form of idiopathic … the
cause of IPF remains elusive and its pathogenesis incompletely understood. In the last decade, …

What we know about the pathogenesis of idiopathic pulmonary fibrosis

S Puglisi, SE Torrisi, R Giuliano… - … in respiratory and …, 2016 - thieme-connect.com
… Although our understanding of the pathogenesis of IPF has improved over the past two … on
pathogenetic mechanisms that we think are crucial for the initiation of the fibrotic process and …

The leading role of epithelial cells in the pathogenesis of idiopathic pulmonary fibrosis

M Selman, A Pardo - Cellular signalling, 2020 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive and devastating interstitial
… normal lung architecture is lost and replaced by fibrotic tissue leading to an irreversible and …

[HTML][HTML] Epithelial–mesenchymal transition in the pathogenesis of idiopathic pulmonary fibrosis

F Salton, MC Volpe, M Confalonieri - Medicina, 2019 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a serious disease of the lung, which leads to extensive
parenchymal scarring and death from respiratory failure. The most accepted hypothesis for …

[HTML][HTML] Pathogenesis of idiopathic pulmonary fibrosis: review of recent findings

E Renzoni, V Srihari, P Sestini - F1000prime reports, 2014 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is likely to result from the interaction between environmental
exposures, including cigarette smoke, and genetic predisposition. This review focuses on …

[HTML][HTML] Inflammatory mechanisms are a minor component of the pathogenesis of idiopathic pulmonary fibrosis

J Gauldie - American Journal of Respiratory and Critical Care …, 2002 - atsjournals.org
… to implicate inflammation as the major pathogenic mechanism because we see patchy areas
… conclusions about the pathogenesis of IPF. Animal models of pulmonary fibrosis have been …