The pathogenesis of organ fibrosis: Focus on necroptosis
M Hao, X Han, Z Yao, H Zhang, M Zhao… - British Journal of …, 2023 - Wiley Online Library
… necroptosis, are closely related to organ fibrosis. Among these programmed cell death …
organ fibrosis. In this review, we summarize the role of necroptosis signalling in organ fibrosis …
organ fibrosis. In this review, we summarize the role of necroptosis signalling in organ fibrosis …
Pathology and natural history of organ fibrosis
J Majo, BM Klinkhammer, P Boor, D Tiniakos - Current opinion in …, 2019 - Elsevier
… of the pathogenesis of pulmonary fibrosis and pathogenetic insights with … of organ and
tissue fibrosis provide hope for successful antifibrotic therapies [1]. Accurate evaluation of fibrosis …
tissue fibrosis provide hope for successful antifibrotic therapies [1]. Accurate evaluation of fibrosis …
Sex related differences in the pathogenesis of organ fibrosis
A Garate-Carrillo, J Gonzalez, G Ceballos… - Translational …, 2020 - Elsevier
… for differences in organ fibrosis as per sex at the epidemiological/clinical, organ and cell
levels. Where clinical evidence regarding sex-based differences in organ fibrosis is either weak …
levels. Where clinical evidence regarding sex-based differences in organ fibrosis is either weak …
Molecular basis of organ fibrosis: potential therapeutic approaches
AK Ghosh, SE Quaggin… - … biology and medicine, 2013 - journals.sagepub.com
… Collectively, these results implicate Smads in the pathogenesis of fibrosis. Selective suppression
of Smad3 or Smad4, but not complete depletion, may be a viable therapeutic approach …
of Smad3 or Smad4, but not complete depletion, may be a viable therapeutic approach …
Resolution of organ fibrosis
… Therefore, it may be possible to harness and amplify the endogenous mechanisms of matrix
resolution to treat organ fibrosis, which develops largely due to repeated or chronic injuries. …
resolution to treat organ fibrosis, which develops largely due to repeated or chronic injuries. …
The novel role of ER protein TXNDC5 in the pathogenesis of organ fibrosis: mechanistic insights and therapeutic implications
CT Hung, YW Tsai, YS Wu, CF Yeh… - Journal of Biomedical …, 2022 - Springer
… , pulmonary, renal and liver fibrosis, showing TXNDC5 is required for the … ameliorates organ
fibrosis and preserves organ function by … strategies targeting TXNDC5 to treat organ fibrosis. …
fibrosis and preserves organ function by … strategies targeting TXNDC5 to treat organ fibrosis. …
Fibrosis in chronic kidney disease: pathogenesis and consequences
S Panizo, L Martínez-Arias, C Alonso-Montes… - International journal of …, 2021 - mdpi.com
… fibrosis. Several systems, molecules and responses involved in the pathogenesis of the
pathological fibrosis of … The pathological fibrotic process of remodeling frequently leads to organ …
pathological fibrosis of … The pathological fibrotic process of remodeling frequently leads to organ …
Direct contribution of epithelium to organ fibrosis: epithelial-mesenchymal transition
M Guarino, A Tosoni, M Nebuloni - Human pathology, 2009 - Elsevier
… in the pathogenesis of fibrotic disorders in these organs. Thus, because of its fibrogenic
potential, the detection of epithelial-mesenchymal transition in biopsy specimens could be useful …
potential, the detection of epithelial-mesenchymal transition in biopsy specimens could be useful …
Pathogenesis of liver fibrosis: role of oxidative stress
G Poli - Molecular aspects of medicine, 2000 - Elsevier
… In vivo studies on the role of ROS and consequent redox imbalance on the pathogenesis
of … reaction and the eventual fibrosis of the organ as induced by long standing cholestasis. …
of … reaction and the eventual fibrosis of the organ as induced by long standing cholestasis. …
[HTML][HTML] Pulmonary fibrosis: pathogenesis, etiology and regulation
… models of fibrosis, including mice overexpressing human TGFβ in the lung, 63 in human
and animal studies of dystrophic muscle fibrosis 64 and in multiple organ fibrosis following …
and animal studies of dystrophic muscle fibrosis 64 and in multiple organ fibrosis following …
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