The meaning of p16ink4a expression in tumors: Functional significance, clinical associations and future developments

AK Witkiewicz, KE Knudsen, AP Dicker, ES Knudsen - Cell cycle, 2011 - Taylor & Francis
… ” of elevated p16 ink4a expression requires ancillary markers (… Not only is p16 ink4a
expression heterogeneous between … of p16 ink4a as a means to categorize particular sub-types of …

High frequency of aberrant p16 (INK4A) expression in human breast cancer.

J Geradts, PA Wilson - The American journal of pathology, 1996 - ncbi.nlm.nih.gov
… approach, we studied the expression of both p16 and pRB in … expression, but only 87 were
interpretable for p16 expression… Only six tumors showed abnormal RB expression. However, …

… and genotyping of human papillomavirus in a Spanish cohort of penile squamous cell carcinomas: correlation with pathologic subtypes, p16INK4a expression, and …

C Ferrándiz-Pulido, E Masferrer, I De Torres… - Journal of the American …, 2013 - Elsevier
… Moreover, we also found a significant correlation between p16 INK4a expression and
poor differentiation grade (P = .03) that was lost when considering only the usual subtype. …

The role of histologic subtype, p16INK4a expression, and presence of human papillomavirus DNA in penile squamous cell carcinoma

J Steinestel, A Al Ghazal, A Arndt, TJ Schnoeller… - BMC cancer, 2015 - Springer
… In contrast to pathological tumour stage, … subtyping as well as p16 INK4a immunostaining
for detection of HR-HPV DNA and propose that ubiquitous nuclear expression of p16 INK4a is …

Value of p16INK4a in the pathology of invasive penile squamous cell carcinomas: a report of 202 cases

AL Cubilla, B Lloveras, M Alejo, O Clavero… - … of surgical pathology, 2011 - journals.lww.com
… We also evaluated HPV and p16 INK4a according to the histologic subtypes of penile SCC.
… that p16 INK4a expression is distinctly related to HPV status and histologic subtype in penile …

Assessment of Correlation Between p16INK4a Staining, Specific Subtype of Human Papillomavirus, and Progression of LSIL/CIN1 Lesions: First Comparative Study

M Razmpoosh, A Sansregret, LL Oligny… - … of Clinical Pathology, 2014 - academic.oup.com
… study suggested, our hypothesis is that it is not the HPV subtype to which an LSIL/CIN1
lesion is associated that provides insight but rather the p16 INK4a expression within the lesion. …

Human papillomavirus infection and immunohistochemical p16INK4a expression as predictors of outcome in penile squamous cell carcinomas

SM Bezerra, A Chaux, MW Ball, SF Faraj, E Munari… - Human pathology, 2015 - Elsevier
… We evaluated the correlation of p16 INK4a expression and HR-… p16 INK4a expression was
assessed by immunohistochemistry (… patients, we found basaloid subtype SCC to show a …

[HTML][HTML] p16INK4a expression in basal-like breast carcinoma

OL Bohn, M Fuertes-Camilo, L Navarro… - … Pathology, 2010 - ncbi.nlm.nih.gov
expression of CKs in basal cancer subtypep16 INK4a expression by immunohistochemistry
on TMAs. This study has shown that strong p16 INK4a positivity coupled with co-expression

Expression of p16INK4a and MIB-1 in relation to histopathology and HPV types in cervical adenocarcinoma

S Muller, C Flores-Staino… - International …, 2008 - spandidos-publications.com
… correlation between p16INK4a expression and subtypes of adenocarcinoma, cancer stage,
recurrence, or patient age (40). Our finding that the level of p16INK4a expression correlates …

The Contrasting Role of p16Ink4A Patterns of Expression in Neuroendocrine and Non-Neuroendocrine Lung Tumors: A Comprehensive Analysis with …

N Fusco, E Guerini-Rocco, A Del Gobbo, R Franco… - PLoS …, 2015 - journals.plos.org
p16 Ink4A expression has been reported in different subtypes of lung cancers; however, its
… performed ex novo the histologic classification and pathologic staging, according to the latest …