Pathological alteration and therapeutic implications of sepsis-induced immune cell apoptosis

C Cao, M Yu, Y Chai - Cell death & disease, 2019 - nature.com
… role of innate and adaptive immune cells in the pathogenesis of sepsis, alterations in their
immune metabolic stage, and the clinical implications and potential therapeutic interventions. …

Dendritic cells in sepsis: pathological alterations and therapeutic implications

DD Wu, T Li, XY Ji - Journal of immunology research, 2017 - Wiley Online Library
… There are many mechanisms involved in the alterations of DCs during sepsis, including
the … in the alterations of DCs in sepsis, as well as further discuss the therapeutic strategies …

Alternative vascularization mechanisms in cancer: Pathology and therapeutic implications

B Döme, MJC Hendrix, S Paku, J Tóvári… - … journal of pathology, 2007 - Elsevier
… Accordingly, recent experimental data indicate that anti-VEGF therapy induces rapid
alterations in tumor vasculature. Within a few hours, EC proliferation is halted, luminal stability …

Pathological mehanisms and disease progression of multiple sclerosis: therapeutic implications

C Bjartmar, RJ Fox - Drugs of Today, 2002 - access.portico.org
… Late onset axonal pathology, such as atrophy or swelling, cytoskeleton alterations, organelle
ac… In myelin proteolipid protein-null mice, the axonal pathology was accompanied with …

Pathological alteration in the choroid plexus of Alzheimer's disease: implication for new therapy approaches

A Krzyzanowska, E Carro - Frontiers in pharmacology, 2012 - frontiersin.org
Morphological alterations of choroid plexus in Alzheimer’s disease (AD) have been
extensively investigated. These changes include epithelial atrophy, thickening of the basement …

… of chagasic cardiomyopathy: the pathologic roles of autonomic abnormalities, autoimmune mechanisms and microvascular changes, and therapeutic implications

MA Rossi, RB Bestetti - Cardiology, 1995 - karger.com
… These processes may be initiated and perpetuated by alterations in the myocardial
microcirculation and by autoimmune factors. The autonomic impairment and/or the chronic fibrosing …

Pathological implication of protein post-translational modifications in cancer

S Pan, R Chen - Molecular aspects of medicine, 2022 - Elsevier
… The pathological implications of PTMs are involved in all … recent studies revealed a novel
pathological role of argonaute 2 (… Alterations in this pathway are widespread across all tumor …

Matrix metalloproteinases in coronary artery disease: clinical and therapeutic implications and pathological significance

MH Tayebjee, GY H Lip… - Current medicinal …, 2005 - ingentaconnect.com
… They are important in normal physiology and also during a range of pathological states.
Only recently has their role in cardiovascular disease been explored and their analysis through …

Glial pathology in bipolar disorder: potential therapeutic implications

XH Dong, XC Zhen - CNS neuroscience & therapeutics, 2015 - Wiley Online Library
… In addition to neuronal alterations, accumulating evidences have revealed the importance
… Postmortem studies have repeatedly demonstrated the alterations in glial cells and its …

Brain metastasis: clinical characteristics, pathological findings and molecular subtyping for therapeutic implications

H Takei, E Rouah, Y Ishida - Brain tumor pathology, 2016 - Springer
… heterogeneous both clinically and pathologically. As members … diagnosis), and unique
pathologic patterns of brain metastases (… on the molecular alterations related to therapy and their …