… of the pathological proteins is largely increased, the MVs system is activated. We found an
enhanced level of pathological proteins in plasma derived MVs from ALS patients compared …

… proteins, such as myelin basic protein (… of patients who have MS. This is supported by
several neuroimaging studies suggesting a diffuse pathology present within the NAWM of patients …

… and pathogenetic mechanisms in multiple sclerosis (MS). Consequently, … for patients in
the relapsing–remitting stage of the disease. This Review summarizes studies on the pathology …

Multiple sclerosis (MS) is a multifactorial demyelinating disease characterized by
neurodegenerative events and autoimmune response against myelin component. Citrullination or …

… demyelinated plaques of multiple sclerosis may reflect a common pathological end point of
… In contrast, major myelin proteins such as myelin basic protein (MBP) and proteolipid protein (…

… with secondary progressive multiple sclerosis (MS). Large … for myelin proteins (eg, proteolipid
protein) is used (B). In … visible by immunocytochemistry for myelin proteins (ERM in F) …

… ) was classified histologically and adjacent sites were homogenized for protein analysis…
sclerosis patients. Assumptions that CSF BSP levels are related to pathology in multiple sclerosis …

… the presence of minor myelin protein degradation products within … myelin proteins (proteolipid
protein, myelin basic protein) are … myelin protein but not minor myelin protein degradation …

… in systemic sclerosis (scleroderma; SSc) and includes chronic kidney disease (CKD). We
have performed analysis of urinary proteins to gain insight into local molecular pathology of …

… understanding of the pathological mechanisms that drive neurodegeneration in individuals
with multiple sclerosis is needed to develop therapies that will effectively treat patients in the …