[HTML][HTML] Pathophysiological basis and rationale for early outpatient treatment of SARS-CoV-2 (COVID-19) infection

PA McCullough, RJ Kelly, G Ruocco, E Lerma… - The American journal of …, 2021 - Elsevier
… The rapidity and highly communicable nature of the SARS-CoV… learned about the
pathophysiology of SARS-CoV-2 infection in … This article outlines key pathophysiological

Angiotensin‐converting enzyme 2 (ACE2), SARSCoV‐2 and the pathophysiology of coronavirus disease 2019 (COVID‐19)

AR Bourgonje, AE Abdulle, W Timens… - The Journal of …, 2020 - Wiley Online Library
… pathologic basis of COVID-19 is essential for our understanding of the pathophysiology of …
findings are mainly observed in specific target organs of SARS-CoV-2, such as the lungs and …

… review of viral characteristics, transmission, pathophysiology, immune response, and management of SARS-CoV-2 and COVID-19 as a basis for controlling the …

CR Triggle, D Bansal, H Ding, MM Islam… - Frontiers in …, 2021 - frontiersin.org
… The swift identification and sequencing of the SARS-CoV-2 genome initiated a … SARS-CoV-2
including mutational changes and implications on infectivity, transmission, pathophysiology, …

SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19

A Tsatsakis, D Calina, L Falzone, D Petrakis… - Food and Chemical …, 2020 - Elsevier
SARS-CoV-2 virus. Considering the multitude of clinical symptoms of COVID-19, the objective
of the present review was to summarize their pathophysiology … on the pathophysiology and …

[HTML][HTML] SARS-CoV-2 pathophysiology and assessment of coronaviruses in CNS diseases with a focus on therapeutic targets

J Vallamkondu, A John, WY Wani, SP Ramadevi… - … (BBA)-Molecular Basis …, 2020 - Elsevier
… discuss the effect of SARS-CoV-2 on CNS … , pathophysiology, theranostics, and autophagy
mechanisms. We will assess the multiorgan failure reported in advanced stages of SARS-CoV

Insights to SARS-CoV-2 life cycle, pathophysiology, and rationalized treatments that target COVID-19 clinical complications

IP Trougakos, K Stamatelopoulos, E Terpos… - Journal of Biomedical …, 2021 - Springer
… Here we discuss SARS-CoV-2 life cycle and a number of approaches aiming to suppress
viral infection rates or propagation; increase virus antigen presentation in order to activate a …

A review on SARS-CoV-2 virology, pathophysiology, animal models, and anti-viral interventions

SN Neerukonda, U Katneni - Pathogens, 2020 - mdpi.com
… lessons learned from SARS-CoV-1 and MERS-CoV studies, … the knowledge pertaining
to SARS-CoV-2 virology that … SARS-CoV-2 virology, clinical features, pathophysiology, and …

Identifying pathophysiological bases of disease in COVID-19

CJ Goldin, R Vázquez, FP Polack… - Translational Medicine …, 2020 - Springer
… S- and SARS CoV S- pseudotyped HIV as well as authentic SARS-CoV and SARS-CoV-2,
even … In the case of SARS-CoV, both mechanisms are independent since ACE2 processing by …

Functional pathophysiology of SARS-CoV-2-induced acute lung injury and clinical implications

NM Habashi, L Camporota… - Journal of applied …, 2021 - journals.physiology.org
… lung pathophysiology of COVID-19 is necessary to determine the treatment of SARS-CoV-2-…
will detail our current understanding of functional lung pathophysiology and how to use this …

SARS-CoV 2; Possible alternative virus receptors and pathophysiological determinants

L Pruimboom - Medical Hypotheses, 2021 - Elsevier
… If sialic acids and especially Neu5Gc emerge as important players in the pathophysiology
of SARS-CoV-2, it may also partially explain the difference in susceptibility between males, …