Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications

CE Berry, JM Hare - The Journal of physiology, 2004 - Wiley Online Library
… participates in the pathophysiology of cardiovascular disease. Biochemical, molecular and
… and pathophysiological role in cardiovascular disease with an emphasis on heart failure. …

[HTML][HTML] Cytochrome c oxidase and nitric oxide in action: molecular mechanisms and pathophysiological implications

P Sarti, E Forte, D Mastronicola, A Giuffrè… - Biochimica et Biophysica …, 2012 - Elsevier
… and NO with some hints about pathophysiological implications. The reactions of interest
are reviewed, with special attention to the molecular mechanisms underlying the effects of NO …

Modulation of the calcium sensitivity of the smooth muscle contractile apparatus: molecular mechanisms, pharmacological and pathophysiological implications

JP Savineau, R Marthan - Fundamental & clinical …, 1997 - Wiley Online Library
… or drugs as well as in some pathophysiological situations. Such … The molecular mechanisms
underlying this modulation are … as pharmacological and pathophysiological implications are …

The role of endothelial dysfunction in peripheral blood nerve barrier: molecular mechanisms and pathophysiological implications

J Maiuolo, M Gliozzi, V Musolino, C Carresi… - … journal of molecular …, 2019 - mdpi.com
The exchange of solutes between the blood and the nerve tissue is mediated by specific and
high selective barriers in order to ensure the integrity of the different compartments of the …

Hypoxia: molecular pathophysiological mechanisms in human diseases

Y Della Rocca, L Fonticoli, TS Rajan, O Trubiani… - Journal of physiology …, 2022 - Springer
… the hypoxic molecular mechanisms reported in different pathological conditions to provide
an overview of hypoxia as a therapeutic agent in regenerative and molecular therapy. …

The Nrf2 in the pathophysiology of the intestine: Molecular mechanisms and therapeutic implications for inflammatory bowel diseases

M Piotrowska, M Swierczynski, J Fichna… - Pharmacological …, 2021 - Elsevier
Nrf2 (nuclear factor erythroid 2-related factor 2) is a stress-responsive transcription factor,
associated with cellular homeostasis. Under normal conditions Nrf2 is kept in the cytoplasm by …

Nuclear receptors and inflammation control: molecular mechanisms and pathophysiological relevance

W Huang, CK Glass - Arteriosclerosis, thrombosis, and vascular …, 2010 - Am Heart Assoc
… of the molecular mechanisms underlying their antiinflammatory functions (illustrated in
Figure 3). Several other members of the nuclear receptor family also contributed significantly to …

Recent advances in the pathophysiology and molecular basis of sepsis-associated organ dysfunction: novel therapeutic implications and challenges

Y Hattori, K Hattori, T Suzuki, N Matsuda - Pharmacology & therapeutics, 2017 - Elsevier
… A better understanding of the molecular mechanisms … at preventing or limiting molecular
events associated with the … of possible pathogenic mechanisms underlying the development …

Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences

N Exner, AK Lutz, C Haass, KF Winklhofer - The EMBO journal, 2012 - embopress.org
… Thus, the major critical issues are whether this phenomenon occurs under pathophysiological
… The molecular mechanism of these interactions and its significance in mammalian models …

Polycystic ovarian syndrome: pathophysiology, molecular aspects and clinical implications

E Diamanti-Kandarakis - Expert Reviews in molecular medicine, 2008 - cambridge.org
… and insulin resistance lie at the pathophysiological core of PCOS. An intriguing concept …
This article reviews the molecular mechanisms known to underlie the ovarian and metabolic …