… a reduction in kidney function. Chronic kidney disease is defined as abnormalities in kidney
damage or … Kidney damage in many kidney diseases can be ascertained by the presence of …

… to understanding their pathophysiological mechanism and assessing prospective treatments
at the preclinical level. This article reviews and updates the pathophysiological knowledge …

… disease (CVD) is a major cause of death in patients with chronic kidney disease (CKD). Both
… In this review, we provide an overview about pathophysiological mechanisms connecting …

… Progression of chronic kidney disease (CKD) involves the recruitment and engagement
of cellular processes originating in specific compartments of the kidney on the one hand and …

… Such novel biomarkers will not only improve risk stratification of patients with DKD, but
will also provide further insights into the complex pathophysiology of the disease, as well as …

… Diabetic kidney disease (DKD), a leading cause of end-stage kidney disease, is the result
of metabolic network alterations in the kidney. Therefore, metabolomics is an effective tool for …

… have led to better understanding of pathophysiology of CKD and would make it …
pathophysiological knowledge of CKD from animal models and human studies, providing new …

… We review here the promising therapeutic avenues based on insights into the mechanisms
of DKD that have recently emerged, including mineralocorticoid receptor antagonists, SGLT2 …

… Chronic kidney disease (CKD) is a pathological condition with high … diseases, mainly
blood hypertension and diabetes. Chronic kidney disease causes various pathophysiological …

… a reduction in kidney function. Chronic kidney disease is defined as abnormalities in kidney
damage or … Kidney damage in many kidney diseases can be ascertained by the presence of …