… signaling pathways and driver oncogenes related to thyroid tumorigenesis, focusing on the
MAPK and PI3K pathways, whose relevance as drivers of oncogenesis in the thyroid gland …

… , and metastasis of thyroid cancer involve various cellular signaling pathways and … pathways
include the Src signaling pathway, JAK–STAT signaling pathway, MAPK signaling pathway…

… β-catenin was not involved in thyroid tumor initiation. Compared with the well-documented
RAS/RAF/MAPK pathway, the β-catenin signal in thyroid cancer is less well understood, and …

… Signaling pathway-related targets provide unprecedented opportunities … cancer. In the
present work, the advances in these signaling pathways and targeted treatments of thyroid cancer …

… of thyroid cancer patients. In the present study, we used a large panel of … thyroid cancer
cell lines to test the therapeutic potential of targeting major signaling pathways to restore thyroid …

… The inhibition of thyroid cancer cell proliferation by PI3K–AKT pathway inhibitors was … in
the PI3K–AKT pathway 108,109 , suggesting that thyroid cancer cells harbouring such genetic …

… of the pathway that … the pathway. The aim of this review is to give an overview of the biology
of RAS/ERK regulators in human cancer highlighting relevant information on thyroid cancer …

The advanced, metastatic differentiated thyroid cancers (DTCs) have a poor prognosis
mainly owing to radioactive iodine (RAI) refractoriness caused by decreased expression of …

… These investigators also found that ZD6474 has a marked inhibitory effect on the growth of
thyroid cancer cell lines with spontaneous RET/PTC rearrangements and also the growth of …

… pathway arrests cells in G1 in thyroid cancer cell lines, and does not compromise viability
[5 • ]. However, only a small number of bona fide thyroid cancer … were not of thyroid origin [37]. …