… markedly inhibited growth of human pancreatic cancer xenografts in athymic mice and also
… PI3/Akt pathways are more important in PDAC these pathways are discussed in this review. …

… Resistance of pancreatic cancer to apoptosis is the key factor … mechanisms specific to
pancreatic cancer should lead to … cell death pathways in pancreatitis and pancreatic cancer with …

… It has been found that YAP and TAZ modulate behavior of pancreatic stellate cells and …
in pancreatic cancer. This review dissects the role of Hippo signaling in pancreatic cancer, …

… on the role of PI3K/AKT/mTOR pathway in PDAC, clinical studies in general have not been
as … /mTOR pathway could provide valuable assets for treatment of pancreatic cancer patients. …

… As the folate pathway plays a supportive role in DNA synthesis and repair pathways, the …
SNPs in genes of the folate metabolic pathway are associated with pancreatic cancer risk. …

… Pancreatic cancer (PC) is one of the highly aggressive malignancies in the United States. It
has been shown that multiple signaling pathways … that Notch signaling pathway plays critical …

… In this regard, analysis of the pancreatic cancer genome has revealed that … to promote
pancreatic cancer growth and metastasis.… Core signaling pathways in human pancreatic cancers …

… 23 biological pathways hypothesized to be relevant to pancreatic cancer and observed a
nominal association between pancreatic cancer and five pathways ( P < 0.05), ie pancreatic …

… In conclusion, pancreatic cancer can originate from acinar cells through acinar to ductal
metaplasia and results from the combination of both genetic events (activation of oncogenic Kras …

… MK binds a variety of different receptors and signalling molecules, and initiates, thereby,
many different higher order signalling pathways in pancreatic cancer cells. These receptors and …