Targeting apoptosis pathways in glioblastoma

G Eisele, M Weller - Cancer letters, 2013 - Elsevier
death and led to cytochrome c release. However, cell death occurred without effector … ,
U343, and MZ-54 glioblastoma cells diminished the extent of cell death induced by (−)-gossypol …

MicroRNAs regulate cell cycle and cell death pathways in glioblastoma

ISEE Sati, I Parhar - International journal of molecular sciences, 2021 - mdpi.com
… the already altered pathways in GBM, including P53, RB, and PI3K-AKT pathways. Furthermore,
… the functions of miRNAs in GBM pathways linked to dysregulation of cell cycle control, …

Glioma cell death: cellcell interactions and signalling networks

HA Leaver, MT Rizzo, IR Whittle - Molecular neurobiology, 2010 - Springer
… In addition to intrinsic mitochondrial and endoplasmic reticulum (ER) pathways of cell
death, extrinsic cell death signalling and sphingolipid signalling have been identified in …

α-Mangostin, a dietary xanthone, induces autophagic cell death by activating the AMP-activated protein kinase pathway in glioblastoma cells

AC Chao, YL Hsu, CK Liu, PL Kuo - Journal of agricultural and …, 2011 - ACS Publications
… -mangostin on cell growth inhibition using in vitro and In Vivo experimental models. We
measured its effect on cell viability and autophagic cell death in two human brain cancer cell lines…

NFκB inhibitors induce cell death in glioblastomas

A Zanotto-Filho, E Braganhol, R Schröder… - Biochemical …, 2011 - Elsevier
… Identification of novel target pathways in glioblastoma (GBM) … GBM cells, and the potential
of NFκB inhibitors as antiglioma agents. NFκB pathway was found overstimulated in GBM cell

Effect of doramectin on programmed cell death pathway in glioma cells

S Du, H Liang, L Zhou, C Chen, R Sun, J Zhang… - Clinical and …, 2023 - Springer
… Based on the results from in vitro studies, we further explore whether DRM can trigger glioma
cell death in vivo. BALB/c nude mice with xenografted C6 cells were employed to evaluate …

[HTML][HTML] Regulation of human glioblastoma cell death by combined treatment of cannabidiol, γ-radiation and small molecule inhibitors of cell signaling pathways

VN Ivanov, J Wu, TK Hei - Oncotarget, 2017 - ncbi.nlm.nih.gov
… as cancer cells in … GBM cells to treatment through signaling pathways induced by the
exogenous cannabinoids that could regulate the signaling cascades initiating death of cancer cells […

The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma

Z Li, NE Mbah, JH Overmeyer, JG Sarver, S George… - BMC cancer, 2019 - Springer
… versus non-cytotoxic vacuole-inducing IPPs in GBM cells, with the goal of defining pathways
essential for triggering cell death. The results indicate that early impairment of glucose …

Downregulation of protein kinase CK2 induces autophagic cell death through modulation of the mTOR and MAPK signaling pathways in human glioblastoma cells

BB Olsen, TH Svenstrup… - … journal of oncology, 2012 - spandidos-publications.com
… leads to cell death in DNA-PK-proficient human glioblastoma cells. We … cell death in two
human glioblastoma cell lines, M059K and T98G, as indicated by the positive staining of cells

Histone deacetylase inhibition and blockade of the glycolytic pathway synergistically induce glioblastoma cell death

V Egler, S Korur, M Failly, JL Boulay, R Imber… - Clinical Cancer …, 2008 - AACR
… In malignant glioma cells, we targeted the histone acetylation pathway with the HDI LAQ824…
of cell death in tumor and immortalized cell lines, and blocked the energy pathway with the …