Treatment of severe psoriasis with anti-CD25 monoclonal antibodies

U Mrowietz, K Zhu, E Christophers - Archives of Dermatology, 2000 - jamanetwork.com
psoriasis vulgaris and generalized pustular psoriasis was first done by using intravenous
anti-CD4 monoclonal antibodies. … Two patients with severe, recalcitrant psoriasis vulgaris were …

Anti-CD4 monoclonal antibody therapy in severe psoriasis

P Morel, JP Revillard, JF Nicolas, J Wijdenes… - Journal of …, 1992 - Elsevier
… In this preliminary open trial, we report that one patient with generalized psoriatic erythroderma
and two patients with chronic extensive psoriasis resistant to other therapies responded …

Treatment of psoriasis with the chimeric monoclonal antibody against tumor necrosis factor α, infliximab

RE Schopf, H Aust, J Knop - Journal of the American Academy of …, 2002 - Elsevier
… We treated 8 patients with severe to moderate psoriasis in an … the PASI as demonstrated in
our patients. This suggests that … of psoriatic skin lesions in our patients was due to infliximab. …

The safety of anti-interleukins monoclonal antibodies for the treatment of psoriasis

S D'Adamio, D Silvaggio, P Lombardo… - Expert Opinion on …, 2019 - Taylor & Francis
… There were 238 pregnancies reported in the Novartis global safety database in a cohort
of patients affected by psoriasis, psoriatic arthritis, and ankylosing spondylitis. It covers any …

Brodalumab, an anti-IL17RA monoclonal antibody, in psoriatic arthritis

PJ Mease, MC Genovese, MW Greenwald… - … England Journal of …, 2014 - Mass Medical Soc
… We randomly assigned patients with active psoriatic arthritis to receive brodalumab (140 or
280 mg subcutaneously) or placebo on day 1 and at weeks 1, 2, 4, 6, 8, and 10. At week 12, …

The treatment of moderate to severe psoriasis with a new anti-CD11a monoclonal antibody

K Papp, R Bissonnette, JG Krueger, W Carey… - Journal of the American …, 2001 - Elsevier
… a humanized monoclonal antibody directed against the CD11a subunit of LFA-1. This study
investigated whether treatment with anti-CD11a antibody provides clinical benefit to patients

Monoclonal antibodies inhibiting IL-12,-23, and-17 for the treatment of psoriasis

C Jeon, S Sekhon, D Yan, L Afifi… - Human vaccines & …, 2017 - Taylor & Francis
… A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis. New Eng J …
human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from …

Advances in the management of psoriasis: monoclonal antibody therapies

D Mehrabi, JB DiCarlo, SL Soon… - International journal of …, 2002 - Wiley Online Library
… the use of monoclonal antibodies in the treatment of psoriasis. … -CD4 antibody has been
studied in the treatment of psoriasis. … in a patient with generalized pustular psoriasis 14 and in a …

Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomised, double-blind, placebo-controlled …

IB McInnes, PJ Mease, B Kirkham, A Kavanaugh… - The Lancet, 2015 - thelancet.com
… In this phase 3 trial, subcutaneous administration of the anti-interleukin-17A monoclonal
antibody secukinumab significantly improved the signs and symptoms of psoriatic arthritis …

Anti–interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis

C Leonardi, R Matheson, C Zachariae… - … England Journal of …, 2012 - Mass Medical Soc
… interleukin-17 with the humanized monoclonal antibody ixekizumab may be an effective
treatment for patients with chronic moderate-to-severe plaque psoriasis. At 12 weeks, significant …