Optimising treatment for COPD–new strategies for combination therapy

T Welte - International journal of clinical practice, 2009 - Wiley Online Library
patients with more severe COPD. This article reviews the evidence for treatment strategies
used in COPD with a focus on combination therapies … Spiriva in Patients With Severe COPD) …

Dual combination therapy versus long‐acting bronchodilators alone for chronic obstructive pulmonary disease (COPD): a systematic review and network meta …

Y Oba, E Keeney, N Ghatehorde… - Cochrane Database of …, 2018 - cochranelibrary.com
… preventing COPD exacerbations based on the rank statistics. Combination therapies appear
… We did not consider triple combination therapy (ie LABA/LAMA/ICS) because it was out of …

[HTML][HTML] Triple versus LAMA/LABA combination therapy for patients with COPD: a systematic review and meta-analysis

A Koarai, M Yamada, T Ichikawa, N Fujino… - Respiratory …, 2021 - Springer
… (LAMA) and long-acting beta-agonist (LABA) combination therapy has been recommended
for patients with COPD who have severe symptoms and a history of exacerbations because it …

[HTML][HTML] Formoterol mono-and combination therapy with tiotropium in patients with COPD: a 6-month study

C Vogelmeier, P Kardos, S Harari, SJM Gans… - Respiratory …, 2008 - Elsevier
Combination therapy and monotherapy showed no clear difference in the … of COPD-related
bad days or exacerbation days. Significantly fewer patients treated with combination therapy

Salmeterol plus theophylline combination therapy in the treatment of COPD

RL ZuWallack, DA Mahler, D Reilly, N Church… - Chest, 2001 - Elsevier
… suggest that combination therapy with salmeterol and theophylline may provide substantial
benefits in both physiologic and clinical outcomes in symptomatic patients with COPD. …

Combination therapy for chronic obstructive pulmonary disease: clinical aspects

JF Donohue - Proceedings of the American Thoracic Society, 2005 - atsjournals.org
… In a study of 20 patients with COPD, Grassi … combination therapy in COPD is for bronchodilator
reversibility testing. In two multicenter, 3-mo, randomized controlled trials, 1,067 patients

Beyond lung function in COPD management: effectiveness of LABA/LAMA combination therapy on patient-centred outcomes

T van der Molen, M Cazzola - Primary Care Respiratory Journal, 2012 - nature.com
… management of COPD and as such, LABA/LAMA combination therapy could play an … and
dyspnoea in patients with COPD. The last item is particularly important in those patients with …

Adding a LAMA to ICS/LABA therapy: a meta-analysis of triple combination therapy in COPD

L Calzetta, M Cazzola, MG Matera, P Rogliani - Chest, 2019 - Elsevier
combination to treat patients with COPD with high blood eosinophil count, 7 whereas, and
as expected, in this meta-analysis, the efficacy of adding a LAMA to an ICS/LABA combination

Combination therapy with long-acting bronchodilators and the risk of major adverse cardiovascular events in patients with COPD: a systematic review and meta …

M Yang, Y Li, Y Jiang, S Guo, JQ He… - European Respiratory …, 2023 - Eur Respiratory Soc
… may increase the risk of cardiovascular disease in patients with COPD. The aim of this … /LABA
combination therapy modifies the risk of cardiovascular disease in patients with COPD. …

Long-acting β2-adrenoceptor agonists or tiotropium bromide for patients with COPD: is combination therapy justified?

RC Tennant, EM Erin, PJ Barnes, TT Hansel - Current opinion in …, 2003 - Elsevier
… benefits of combination therapies in the treatment of COPD. Combination therapy with inhaled
… have shown that this combination in a single inhaler is beneficial in defined populations of …