[HTML][HTML] EGFR mutation, smoking, and gender in advanced lung adenocarcinoma

CH Tseng, CJ Chiang, JS Tseng, TY Yang, KH Hsu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… reimbursing advanced EGFR-mutant lung adenocarcinoma patients receiving EGFR-TKI
as … , every EGFR-mutant patient in the present study had an equal chance to receive EGFR-…

Analyzing EGFR mutations and their association with clinicopathological characteristics and prognosis of patients with lung adenocarcinoma

X Zhou, L Cai, J Liu, X Hua, Y Zhang… - Oncology …, 2018 - spandidos-publications.com
patients with lung adenocarcinoma who had not undergone prior radiotherapy or chemotherapy.
EGFR mutations … present study, EGFR mutations in lung adenocarcinoma patients were …

[HTML][HTML] Dynamic plasma EGFR mutation status as a predictor of EGFR-TKI efficacy in patients with EGFR-mutant lung adenocarcinoma

JS Tseng, TY Yang, CR Tsai, KC Chen, KH Hsu… - Journal of thoracic …, 2015 - Elsevier
patients according to their plasma EGFR mutation status. All 25 patients without detectable
plasma EGFR mutations … negative for plasma EGFR mutations after EGFR-TKI treatment and …

[HTML][HTML] Prognostic and therapeutic implications of EGFR and KRAS mutations in resected lung adenocarcinoma

JL Marks, S Broderick, Q Zhou, D Chitale, AR Li… - Journal of thoracic …, 2008 - Elsevier
… for responses to EGFR TKIs, EGFR mutations also seem to … patients with untreated advanced
non-small cell lung cancer (… erlotinib, patients with EGFR mutations showed significantly …

[HTML][HTML] Five-year survival in EGFR-mutant metastatic lung adenocarcinoma treated with EGFR-TKIs

JJ Lin, S Cardarella, CA Lydon, SE Dahlberg… - Journal of Thoracic …, 2016 - Elsevier
… specific EGFR-mutant metastatic adenocarcinoma population … patients with EGFR-mutant
metastatic lung adenocarcinoma treated with a Food and Drug Administration–approved EGFR

Clinical and pathological characteristics of EGFR mutation in operable early-stage lung adenocarcinoma

M Yotsukura, H Yasuda, T Shigenobu, K Kaseda… - Lung Cancer, 2017 - Elsevier
… Among tumors with EGFR mutation, there was no difference in OS (p = 0.140) … EGFR
mutation status was not a prognostic indicator after surgery in early-stage lung adenocarcinoma

[HTML][HTML] A retrospective analysis in patients with EGFR-mutant lung adenocarcinoma: is EGFR mutation associated with a higher incidence of brain metastasis?

G Han, J Bi, W Tan, X Wei, X Wang, X Ying, X Guo… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… prognostic for patients with lung adenocarcinoma. We aimed to explore the potential association
EGFR mutation and the risk of BM in pulmonary adenocarcinoma patients. Data of 234 …

… Resistance to Epidermal Growth Factor Receptor Kinase Inhibitors Associated with a Novel T854A Mutation in a Patient with EGFR-Mutant Lung Adenocarcinoma

J Bean, GJ Riely, M Balak, JL Marks, M Ladanyi… - Clinical cancer …, 2008 - AACR
… second-site exon 21 EGFR mutation, T854A, in tumor cells from a patient with EGFR-mutant
lung adenocarcinoma and acquired resistance to EGFR tyrosine kinase inhibitors. The …

[HTML][HTML] EGFR-mutated lung cancer: a paradigm of molecular oncology

Z Zhang, AL Stiegler, TJ Boggon, S Kobayashi… - Oncotarget, 2010 - ncbi.nlm.nih.gov
… cell lung cancer and the subsequent discovery of activating EGFR mutations have led to an
… of knowledge in the fields of EGFR biology, targeted therapeutics and lung cancer research. …

RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer

MJ Niederst, LV Sequist, JT Poirier, CH Mermel… - Nature …, 2015 - nature.com
… To determine whether EGFR expression is commonly lost in EGFR mutant lung cancers
that transform to SCLC, we performed IHC analysis on seven resistant cases of EGFR mutant