Challenges and controversies in management of pancreatic neuroendocrine tumours in patients with MEN1

CJ Yates, PJ Newey, RV Thakker - The Lancet Diabetes & …, 2015 - thelancet.com
… Multiple endocrine neoplasia type 1 (MEN1), an autosomal dominant disorder, is … of pancreatic
neuroendocrine tumours (P-NETs) in association with parathyroid and pituitary tumours. P…

[HTML][HTML] Management of pancreatic neuroendocrine tumors in patients with MEN 1

SM Sadowski, F Triponez - Gland surgery, 2015 - ncbi.nlm.nih.gov
… was found in patients with larger tumors. This review summarizes key concepts in
managing PNETs in patients with MEN1. Keywords: Pancreatic neuroendocrine tumors (PNETs), …

Higher risk of aggressive pancreatic neuroendocrine tumors in MEN1 patients with MEN1 mutations affecting the CHES1 interacting MENIN domain

DK Bartsch, EP Slater, M Albers… - The Journal of …, 2014 - academic.oup.com
MEN1 patients with MEN1 mutations leading to CHES1-… MEN1) is an autosomal dominant
inherited disorder classically characterized by the development of neuroendocrine neoplasms

Long-term natural course of small nonfunctional pancreatic neuroendocrine tumors in MEN1—results from the Dutch MEN1 Study Group

CRC Pieterman, JM De Laat, JWR Twisk… - The Journal of …, 2017 - academic.oup.com
… Pancreatic neuroendocrine tumors (pNETs) are highly prevalent in patients with multiple
endocrine neoplasia type 1 (MEN1), and metastatic disease is an important cause of …

The management of neuroendocrine tumors of the lung in MEN1: results from the Dutch MEN1 study group

MFM Van Den Broek, JM De Laat… - The Journal of …, 2021 - academic.oup.com
tumors at a young age, with primary hyperparathyroidism due to parathyroid adenomas,
neuroendocrine tumors (… MEN1 patients are also at risk of adrenal tumors, lung NETs, thymic …

Somatostatin analogue therapy in MEN1-related pancreatic neuroendocrine tumors from evidence to clinical practice: A systematic review

A La Salvia, F Sesti, C Grinzato, R Mazzilli… - Pharmaceuticals, 2021 - mdpi.com
… We selected 20 studies with a pooled population of 105 MEN1 patients with pNENs. Females
were 58.5%, median age was 44 years (18–73). TNM stage at diagnosis was stage I–II in …

Global gene expression in neuroendocrine tumors from patients with the MEN1 syndrome

WG Dilley, S Kalyanaraman, S Verma, JP Cobb… - Molecular Cancer, 2005 - Springer
Patients and Controls Eight neuroendocrine tumors from six MEN1 patients were included
in this study. The patient ages were 19, 22, 42, 51, 57, and 57 years at the time of surgery (…

Histologically proven bronchial neuroendocrine tumors in MEN1: a GTE 51-case cohort study

P Lecomte, C Binquet, M Le Bras, A Tabarin… - World Journal of …, 2018 - Springer
… -related br-NETs do not significantly decrease overall survival of MEN1 patients; (6)
operated and metastasis-free patients had better survival; (7) surgery is safe as there were no …

Natural course and survival of neuroendocrine tumors of thymus and lung in MEN1 patients

JM De Laat, CR Pieterman… - The Journal of …, 2014 - academic.oup.com
… , patients were selected from the Dutch national MEN1 database of the DutchMEN1 Study
Group (DMSG). All MEN1 patients … In each UMC, MEN1 patients were identified by a standard …

Prognostic factors for the outcome of nonfunctioning pancreatic neuroendocrine tumors in MEN1: a systematic review of literature

SM Sadowski, CRC Pieterman… - … -related cancer, 2020 - erc.bioscientifica.com
… conclude that in patients with MEN1 undergoing resection of … neuroendocrine and non-neuroendocrine
tumors. This necessitates validation of evidence from sporadic pNETs in MEN1