Synovial inflammation in osteoarthritis progression

E Sanchez-Lopez, R Coras, A Torres… - Nature Reviews …, 2022 - nature.com
… 2) and cell types associated with synovial inflammation in OA. We focus on the mediators
of synovial inflammation (Fig. 3), the crosstalk between synovial cells (Fig. 4) and their clinical …

[PDF][PDF] Synovial inflammation in patients with different stages of knee osteoarthritis

R Ene, RD Sinescu, P Ene, MM Cîrstoiu… - Rom J Morphol …, 2015 - academia.edu
osteoarthritis (OA) is commonly described as a non-inflammatory joint disease, synovial
inflammationSynovial histological changes include synovial hypertrophy and hyperplasia with a …

[HTML][HTML] Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review

BJE De Lange-Brokaar, A Ioan-Facsinay… - Osteoarthritis and …, 2012 - Elsevier
osteoarthritis (OA) is considered a non-inflammatory condition, it is widely accepted that synovial
inflammation … knowledge of inflammatory properties, immune cells and their cytokines in …

Synovial tissue inflammation in early and late osteoarthritis

MJ Benito, DJ Veale, O FitzGerald… - Annals of the …, 2005 - ard.bmj.com
… In this study, synovial tissue from patients with RA and other inflammatory … of synovitis in
OA might be similar to that of inflammatory arthropathies, but that the intensity of inflammation in …

[HTML][HTML] Correlation between systemic markers of inflammation and local synovitis in knee osteoarthritis

M Babaei, Y Javadian, H Narimani… - Caspian journal of …, 2019 - ncbi.nlm.nih.gov
… At present, no serum marker has been shown linking to knee synovitis in KOA. … of inflammation,
this study aimed to determine the association of systemic inflammation with local synovitis

Importance of synovitis in osteoarthritis: evidence for the use of glycosaminoglycans against synovial inflammation

Y Henrotin, C Lambert, P Richette - Seminars in arthritis and rheumatism, 2014 - Elsevier
synovial inflammation in OA, this review documents how selected GAGs, ie, chondroitin
sulfate, glucosamine, and hyaluronic acid could be potent interventions against synovitis in OA. …

… marrow mesenchymal stromal cell treatment in patients with osteoarthritis results in overall improvement in pain and symptoms and reduces synovial inflammation

J Chahal, A Gómez-Aristizábal… - Stem cells …, 2019 - academic.oup.com
… content, cartilage degradation, synovial inflammation, joint … synovial inflammation that
is potentially more effective at the 50 million BM-MSC cell dose. Using a panel of anti-inflammatory

[HTML][HTML] Elevated high-sensitivity C-reactive protein levels are associated with local inflammatory findings in patients with osteoarthritis

AD Pearle, CR Scanzello, S George, LA Mandl… - Osteoarthritis and …, 2007 - Elsevier
… These results suggest that systemic hsCRP levels reflect synovial inflammation in OA
patients, perhaps by means of synovial IL-6 production. Future studies are needed to clarify how …

[HTML][HTML] Synovial tissue metabolomic profiling reveal biomarkers of synovial inflammation in patients with osteoarthritis

JD Murillo-Saich, R Coras, R Meyer, C Llorente… - Osteoarthritis and …, 2022 - Elsevier
… in both the synovial fluid (SF) and serum of osteoarthritis subjects. Our … synovial tissue (ST)
and SF of individuals with osteoarthritis (OA) and its association with synovial inflammation

[HTML][HTML] The importance of synovial inflammation in osteoarthritis: current evidence from imaging assessments and clinical trials

X Wang, DJ Hunter, X Jin, C Ding - Osteoarthritis and cartilage, 2018 - Elsevier
… and characterisation of synovitis (eg, imaging or histologic assessment), solid evidence
underpins the association between synovial inflammation and symptoms in patients with knee …