… level of synovial tissue inflammation for future … for patient assessment. Several investigators
have sought to optimize methods to score synovial inflammation using H&E-stained synovial …

… of aggrecanases in the osteoarthritis synovium. We established a model of cultures of synovial
cells from digested osteoarthritis synovium derived from patients undergoing knee or hip …

Results The concentrations of IL-18 and IL-20 were statistically significantly higher in serum
of patients with OA than in the control group (106.00±189.76 pg/ml vs. 16.73±16.99 pg/ml, p…

… -inflammatory state associated with obesity might all contribute to OA synovial inflammation
… In addition, inflamed tissues in patients with OA express proalgesic molecules such as NGF, …

… effects of PRPr on synovial inflammation. Another group of 22 mice were used to assess the
presence of pain up to 3 weeks and to assess synovial inflammation and cartilage damage …

… synovial inflammation (synovitis) and bone marrow lesions in explaining pain. There is
evidence also that altered sensitivity of the nerves which supply the knee or within the CNS may …

… the cytokines were produced by synovial cells (39% … synovial fluid confirmed. The synoviocytes
producing IL-1beta (a classic pathogenic cytokine in osteoarthritis), mainly inflammatory …

… patients revealed synovial inflammation, measured by synovial hypertrophy and synovial …
A third study found that mice deficient in CCR2 or CCL2 had decreased synovial inflammation …

… Here we discuss recent findings on the involvement of synovial inflammation and
particularly the role of synovial macrophages in OA pathogenesis. Understanding macrophage …

… We speculate that the pro-inflammatory response in certain patients lacks adequate control
… synovial inflammation in symptom development may support therapeutic targeting of synovial …