[PDF][PDF] Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets

JP Pelletier, J Martel‐Pelletier… - Arthritis & Rheumatism …, 2001 - stem-art.com
… Moreover, is synovial inflammation only relevant during the “flare” of the disease or is it an …
regarding synovial inflammation and OA. First, what evidence do we have that inflammation is …

Pain in hand osteoarthritis is associated with inflammation: the value of ultrasound

MC Kortekaas, WY Kwok, M Reijnierse, I Watt… - Annals of the …, 2010 - ard.bmj.com
… However, that study was performed in patients with … of inflammatory signs in several HOA
subsets are warranted. On average, patients in this study had fewer joints showing GS synovitis

Characterization of the proinflammatory profile of synovial fluid‐derived exosomes of patients with osteoarthritis

R Domenis, R Zanutel, F Caponnetto… - … of Inflammation, 2017 - Wiley Online Library
synovial fluid- (SF-) derived exosomes of patients with … Extracellular vesicles (EVs) have
been isolated from inflamed … the release of several inflammatory cytokines and chemokines and …

Serum YKL-40 levels in healthy children and adults. Comparison with serum and synovial fluid levels of YKL-40 in patients with osteoarthritis or trauma of the knee …

JS Johansen, J Hvolris, M Hansen, V Backer… - …, 1996 - academic.oup.com
… and the degree of synovial inflammation in the knee joint. … blood and synovial fluid in a small
study of patients with different … synovial fluid from knee joints of patients with osteoarthritis or …

[HTML][HTML] Inflammatory biomarkers in osteoarthritis

HN Daghestani, VB Kraus - Osteoarthritis and cartilage, 2015 - Elsevier
Inflammatory osteoarthritis (OA) is a debilitating and highly … that inflammatory and destructive
responses of the synovium play a major role in OA 1 . Moreover, the role of inflammation in …

Macroscopic and microscopic features of synovial membrane inflammation in the osteoarthritic knee: correlating magnetic resonance imaging findings with disease …

D Loeuille, I Chary‐Valckenaere… - Arthritis & …, 2005 - Wiley Online Library
… evaluate synovial inflammation coupled with the failure of conventional radiography to depict
early cartilage lesions. Synovitis is an important characteristic of chronic inflammatory joint …

Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients.

IB McInnes, BP Leung, M Field, XQ Wei… - The Journal of …, 1996 - rupress.org
… by primary synovial cultures from rheumatoid (RA) and osteoarthritis patients. Increased NO
… arthritides, but may reflect a nonspecific synovial response to injury or inflammation with …

… determination of steroid hormone receptor positive cells in the synovium of patients with rheumatoid arthritis and osteoarthritis: is there a link to inflammation?

S Capellino, B Riepl, L Rauch, P Angele… - Annals of the …, 2007 - ard.bmj.com
… receptors might also influence the inflammatory process. Receptors of these steroid
hormones have been identified in synovial cells in patients with inflammatory joint diseases. …

[HTML][HTML] Ultrasonographic evidence of inflammation is frequent in hands of patients with erosive osteoarthritis

M Vlychou, A Koutroumpas, K Malizos… - Osteoarthritis and …, 2009 - Elsevier
… supports the concept of EOA as an inflammatory arthritis. The detection of synovial inflammation
and tenosynovitis in the vast majority of patients with EOA suggests that new treatment …

[HTML][HTML] Guiding synovial inflammation by macrophage phenotype modulation: an in vitro study towards a therapy for osteoarthritis

L Utomo, GJVM van Osch, Y Bayon, JAN Verhaar… - Osteoarthritis and …, 2016 - Elsevier
inflammatory joint diseases, led to the hypothesis that a potentially specific strategy to control
inflammation … Therefore, the aim of this study was to guide synovial inflammation with four …