Comparative expression analyses of pro‐versus anti‐inflammatory mediators within synovium of patients with joint trauma, osteoarthritis, and rheumatoid arthritis

MA Al-Madol, M Shaqura, T John, R Likar… - … of Inflammation, 2017 - Wiley Online Library
… and anabolic processes by anti-inflammatory mediators. Here we … inflammatory mediators
in synovium of patients with diagnostic arthroscopy (control), joint trauma (JT), osteoarthritis

Phenotypic characterization of inflammatory cells from osteoarthritic synovium and synovial fluids

MK Haynes, EL Hume, JB Smith - Clinical Immunology, 2002 - Elsevier
… progressing patients from nonprogressing patients would be of great help to clinicians and
their patients. Reasons for these differences remain undetermined, but synovial inflammation

Decreased pain and synovial inflammation after etanercept therapy in patients with reactive and undifferentiated arthritis: an open‐label trial

SD Flagg, R Meador, E Hsia… - Arthritis Care & …, 2005 - Wiley Online Library
… in 3 patients; 2 patients became PCR negative on etanercept. Five of 6 patients with
adequate synovial biopsy specimens showed improvement, but not normalization of histology. …

Induction of an inflammatory and prodegradative phenotype in autologous fibroblast‐like synoviocytes by the infrapatellar fat pad from patients with knee osteoarthritis

F Eymard, A Pigenet, D Citadelle… - Arthritis & …, 2014 - Wiley Online Library
… release of cartilage degradation products, which activate synovial resident cells (6). However,
synovial membrane, we hypothesized that the IFP may contribute to synovial inflammation

Association of pain in knee osteoarthritis with distinct patterns of synovitis

BJE de Lange‐Brokaar, A Ioan‐Facsinay… - Arthritis & …, 2015 - Wiley Online Library
… In our study, component 2 was characterized by synovial inflammation at the ACL, medial
parameniscal site, suprapatellar site, and intercondylar site. We did not find an association of …

IL-6 secretion in osteoarthritis patients is mediated by chondrocyte-synovial fibroblast cross-talk and is enhanced by obesity

MJ Pearson, D Herndler-Brandstetter, MA Tariq… - Scientific reports, 2017 - nature.com
… In addition, the leptin-enhanced synovial inflammation we report here provides further
support for the metabolic (non-mechanical load) effect of obesity on joint disease, and could …

[HTML][HTML] A new non-invasive method to assess synovitis severity in relation to symptoms and cartilage volume loss in knee osteoarthritis patients using MRI

JP Pelletier, JP Raynauld, F Abram, B Haraoui… - Osteoarthritis and …, 2008 - Elsevier
… The role of synovial inflammation in osteoarthritis (OA) is of … that lead to synovial inflammation
remain largely unknown. The … by the synovium, which triggers a secondary inflammation

Another look at osteoarthritis.

EC Huskisson, PA Dieppe, AK Tucker… - Annals of the rheumatic …, 1979 - ard.bmj.com
… Evidence of inflammation was often found in patients with osteoarthritis and included
morning stiffness, redness of distal interphalangeal joints, warmth, and effusions in the knees. In …

Extensive cytokine analysis in synovial fluid of osteoarthritis patients

L Yang, Z Chen, H Guo, Z Wang, K Sun, X Yang… - Cytokine, 2021 - Elsevier
… proteomic biomarkers in synovial fluid to improve diagnosis and therapy of OA patients.
Methods: … , composed of inflammatory cells and proteins released from synovial fibroblasts, the …

Osteoarthritis and inflammation: a serious disease with overlapping phenotypic patterns

F Berenbaum, C Walker - Postgraduate medicine, 2020 - Taylor & Francis
synovial inflammation (synovitis) which leads to the common symptoms and clinical signs of
OA [Citation23]. In some patients, the … encounter synovial tissue this leads to inflammation […