Elevated plasma levels of hyaluronate in patients with osteoarthritis and rheumatoid arthritis

RL Goldberg, JP Huff, ME Lenz… - … : Official Journal of …, 1991 - Wiley Online Library
… in part the contention that plasma HA may be unique as a marker, in that it may be a
reflection of synovial involvement and inflammation, rather than only of inflammation, in arthritis. …

[HTML][HTML] … of nonsteroidal anti-inflammatory drugs on clinical outcomes, synovial fluid cytokine concentration and signal transduction pathways in knee osteoarthritis. A …

L Gallelli, O Galasso, D Falcone, S Southworth… - Osteoarthritis and …, 2013 - Elsevier
… -inflammatory cytokines and the clinical status of OA patientssynovial fluid and the pain
and functional status of patients … pathways in the synovial membrane were also investigated. …

[PDF][PDF] Human knee synovial fluid cytokines correlated with grade of knee osteoarthritis

CT Vangsness Jr, WS Burke… - Bulletin of the NYU …, 2011 - researchgate.net
… by antibody staining among arthritic patients found by Smith and colleagues.No correction
could be made in this study with respect to tissue inflammation on biopsies that were graded …

[HTML][HTML] … whole knee semi-quantitative scoring method correlates with histologic and macroscopic features of synovial tissue inflammation in knee osteoarthritis

BJE de Lange-Brokaar, A Ioan-Facsinay, E Yusuf… - Osteoarthritis and …, 2014 - Elsevier
inflammatory condition. More recently, however, it became evident that synovial inflammation
… Although the biological processes underlying the appearance of synovial inflammation are …

[HTML][HTML] Synovial cytokines significantly correlate with osteoarthritis-related knee pain and disability: inflammatory mediators of potential clinical relevance

TA Nees, N Rosshirt, JA Zhang, T Reiner… - Journal of clinical …, 2019 - mdpi.com
… This study provides an extensive profile of synovial inflammatory mediators in knee OA
and … inflammatory pattern is characterized by a wide array of both anti- and pro-inflammatory

What drives osteoarthritis?—synovial versus subchondral bone pathology

T Hügle, J Geurts - Rheumatology, 2017 - academic.oup.com
Inflammatory symptoms such as joint effusion or articular stiffness are common in OA and
synovial inflammation detected by sonography occurs in more than half of the patients with …

[HTML][HTML] Characterization of synovial mast cells in knee osteoarthritis: association with clinical parameters

BJE de Lange-Brokaar, M Kloppenburg… - Osteoarthritis and …, 2016 - Elsevier
Synovial tissues of 56 symptomatic OA and 49 RA patients were obtained. Two to three
paraffin … synovial inflammation Patients with OA had lower histological synovitis scores than …

Imaging of synovitis in osteoarthritis: current status and outlook

D Hayashi, FW Roemer, A Katur, DT Felson… - Seminars in arthritis and …, 2011 - Elsevier
… In summary, CE-MRI seems to be a more reliable and valid measure of synovial inflammation
compared with non-CE-MRI and could be useful in clinical trials as a marker of therapeutic …

Urocortin expression in synovium of patients with rheumatoid arthritis and osteoarthritis: relation to inflammatory activity

M Kohno, Y Kawahito, Y Tsubouchi… - The Journal of …, 2001 - academic.oup.com
… of urocortin in peripheral inflammatory sites have … synovial tissues of patients with RA and
OA. Moreover, we examined the relation between the expression of urocortin and inflammatory

Is synovial macrophage activation the inflammatory link between obesity and osteoarthritis?

ARJ Sun, T Friis, S Sekar, R Crawford, Y Xiao… - Current rheumatology …, 2016 - Springer
… The role for inflammatory cells and cytokines is evident in both MetS and OA patients;
however, in contrast with rheumatoid arthritis (RA), synovitis (synovial inflammation) is not …