Differential metabotypes in synovial fibroblasts and synovial fluid in hip osteoarthritis patients support inflammatory responses

H Farah, SN Wijesinghe, T Nicholson… - International journal of …, 2022 - mdpi.com
patients not selected for exhibiting overt synovitis. Indeed, we have previously reported that
patients who are obese exhibit a more inflammatory synovial fluid profile than OA patients

Osteoarthritis, angiogenesis and inflammation

CS Bonnet, DA Walsh - Rheumatology, 2005 - academic.oup.com
patients with end-stage disease undergoing joint replacement surgery [2, 9, 10]. Synovial
inflammation … Even when inflammation is secondary to other processes within the osteoarthritic …

Cross sectional evaluation of biochemical markers of bone, cartilage, and synovial tissue metabolism in patients with knee osteoarthritis: relations with disease activity …

P Garnero, M Piperno, E Gineyts, S Christgau… - Annals of the …, 2001 - ard.bmj.com
… markers of type II collagen and synovial tissue destruction respectively—disease activity
and the severity of joint destruction in patients with knee osteoarthritis (OA). The clinical …

[HTML][HTML] Differential distribution of adipokines between serum and synovial fluid in patients with osteoarthritis. Contribution of joint tissues to their articular production

N Presle, P Pottie, H Dumond, C Guillaume… - Osteoarthritis and …, 2006 - Elsevier
… serum and synovial fluid (SF) samples of patients with osteoarthritis (… patients. The
levels of adipokines were also determined in conditioned media from cultured joint tissues (synovium, …

Inflammation in osteoarthritis: is it time to dampen the alarm (in) in this debilitating disease?

MHJ Van den Bosch - Clinical & Experimental Immunology, 2019 - academic.oup.com
… is present and actively involved in the pathogenesis of osteoarthritis (OA). The most broadly
synovial inflammation by stimulation of cells in the synovial lining. Activated synovial cells …

Obesity, inflammation, and immune system in osteoarthritis

U Nedunchezhiyan, I Varughese, ARJ Sun… - Frontiers in …, 2022 - frontiersin.org
… of synovial macrophages in OA and other inflammatory arthritis… the development of OA-like
synovial insulin resistance (44), … In a study to assess the synovial inflammation between early …

[HTML][HTML] Insulin resistance: releasing the brakes on synovial inflammation and osteoarthritis?

TM Griffin, KM Huffman - Arthritis & Rheumatology (Hoboken, NJ), 2016 - ncbi.nlm.nih.gov
… of synovial inflammation and catabolism. Consequently, the development of synovial insulin
… insulin to suppress the production of inflammatory and catabolic mediators that promote OA. …

[HTML][HTML] Magnetic resonance imaging in osteoarthritis: which method best reflects synovial membrane inflammation?: Correlations with clinical, macroscopic and …

D Loeuille, AC Rat, JC Goebel, J Champigneulle… - Osteoarthritis and …, 2009 - Elsevier
… The volume of synovium is determined with low, intermediate and high-speed enhancement
synovitis score”. The objective of the work is to study synovial membrane (SM) inflammation

Arthroscopic and immunohistologic characterization of knee joint synovitis in osteoarthritis

S Lindblad, E Hedfors - … & Rheumatism: Official Journal of the …, 1987 - Wiley Online Library
osteoarthritis was corroborated by arthroscopic evidence of characteristic cartilage degeneration.
Signs of inflammation were confined to areas of the synovial … the synovial inflammation

Metabolic regulation of inflammation in osteoarthritis

F Berenbaum, TM Griffin… - Arthritis & rheumatology, 2017 - Wiley Online Library
synovial inflammation 56. Surprisingly, though, infrapatellar fat pad size is negatively
associated with knee OA prevalence and risk of progression 57. These findings imply that a larger …