TNF inhibition rapidly down-regulates multiple proinflammatory pathways in psoriasis plaques

AB Gottlieb, F Chamian, S Masud… - The Journal of …, 2005 - journals.aai.org
… obtained in this study is much more detailed than any previous study of a TNF inhibitor in
human disease, and it is conceptually different from most models of TNF inhibition in arthritis. …

Effectiveness and drug survival of TNF-inhibitors in the treatment of psoriatic arthritis: a prospective cohort study

K Aaltonen, A Heinonen, J Joensuu… - Seminars in Arthritis and …, 2017 - Elsevier
… In this study, we found that 68% and 51% of PsA patients treated with TNF-inhibitors as
their first bDMARD reached at least moderate EULAR and ACR20 response after 6 months of …

Treatment Resistance to TNFα Inhibitors in Patients with Psoriasis

A Gholami, A Vafaeian, M Daneshpazhooh… - Dermatologic …, 2023 - Wiley Online Library
… In this study, patients with moderate-to-severetreatment-resistant psoriasis who were …
A total of 131 biologic-naïve patients with psoriasis treated with anti-TNF-α were included in …

Guselkumab in patients with active psoriatic arthritis who were biologic-naive or had previously received TNFα inhibitor treatment (DISCOVER-1): a double-blind …

A Deodhar, PS Helliwell, WH Boehncke, AP Kollmeier… - The Lancet, 2020 - thelancet.com
… of standard therapies, including TNF inhibitors. Although TNF inhibitors are frequently
chosen as the first biologic therapy for patients with psoriatic arthritis, a substantial proportion of …

Initiation of TNF inhibitor therapy and change in physiologic measures in psoriasis

JJ Wu, L Liu, MM Asgari, JR Curtis… - Journal of the …, 2014 - Wiley Online Library
… index (BMI) before and after start of TNF inhibitors or MTX. The study was restricted to … patient
served as their own control. In addition, we compared TNF inhibitor patients to MTX patients

JAK inhibitors: treatment efficacy and safety profile in patients with psoriasis

L Hsu, AW Armstrong - Journal of immunology research, 2014 - Wiley Online Library
… clinical response in patients who were refractory to treatments such as methotrexate
monotherapy, disease-modifying antirheumatic drugs (DMARDs), or TNF inhibitors in phase II and …

[PDF][PDF] Tumor necrosis factor inhibitors in psoriasis: an update

FA Kerdel, BE Strober - Semin Cutan Med Surg, 2014 - scmsjournal.com
TNF inhibitors, golimumab and certolizumab pegol, have shown efficacy against plaque
psoriasis in clinical trials of psoriatic … and safety of the TNF inhibitors in psoriasis, with special …

Psoriasis and pustular dermatitis triggered by TNFinhibitors in patients with rheumatologic conditions

GC de Gannes, M Ghoreishi, J Pope… - Archives of …, 2007 - jamanetwork.com
… evidence of psoriasis in 15 patients treated with TNFinhibitors for a variety of rheumatologic
conditions. We introduce the hypothesis that the cross-regulation between TNF-α and IFN …

Efficacy, safety, and drug survival of IL-23, IL-17, and TNF-alpha inhibitors for psoriasis treatment: a retrospective study

P Dapavo, N Siliquini, L Mastorino… - Journal of …, 2022 - Taylor & Francis
… We reviewed the clinical records of patients with moderate to severe psoriasis treated with
… All patients were diagnosed with psoriasis by experienced dermatologists with clinical and …

An increased risk of non‐melanoma skin cancer during TNFinhibitor treatment in psoriasis patients compared to rheumatoid arthritis patients probably relates to …

PPM Van Lümig, SP Menting… - Journal of the …, 2015 - Wiley Online Library
… and a group of RA patients treated with similar anti-TNF regimens were compared. The aim
… between psoriasis and RA patients with respect to the duration of TNF-inhibitor therapy until …