… Given that these results were derived from a population of ICU patients with severe sepsis, …
-lactam antibiotics is likely to be beneficial for patients with a high level of illness severity not …

… in adequate serum drug concentrations in patients with severe sepsis and septic shock. …
on a more severe population of patients, suffering from severe sepsis and septic shock, with …

… -lactamases (ESBL)-producing Enterobacteriaceae (E). The … of outcome in septic patients
with bloodstream infection (BSI) … -E in patients who developed severe sepsis or septic shock …

… In this individual patient data meta-analysis of a large critical care patient population with
severe sepsis, we found that administration of β-lactam antibiotics by continuous infusion was …

… intermittent infusion in patients with severe sepsis. The aim of the β-Lactam Infusion Group
(… and intermittent β-lactam antibiotic infusion in patients with severe sepsis in alive intensive …

… optimal dosing of beta-lactam antibiotics has the potential to improve the outcome for critically
ill patients with severe sepsis. Beta-lactam antibiotics are administered almost exclusively …

… Patients who present with severe sepsis or septic … severe sepsis happened before the
initiation of the antimicrobial therapy. Hence, the observed association between disease severity …

… Our policy in patients with severe sepsis or septic shock is to add an aminoglycoside, rather
than a quinolone, to a beta-lactam ( 47 ). In vitro synergism has been demonstrated between …

… between-lactam concentrations and neurological alterations in septic ICU patients. …
Conclusions: We found a correlation between high β-lactam trough concentrations and increased …

… and between patients. The DALI study, a large multicenter prospective study evaluated
248 ICU patients treated for infection with beta-lactams and found large variations on beta-lactam …