Signaling pathways for PC12 cell differentiation: making the right connections
… by GPCR and RTK activation in PC12 cells, through both CRE-… genes in PC12 cells that is
required for differentiation may also … PC12 cells continue to be an important model system by …
required for differentiation may also … PC12 cells continue to be an important model system by …
Assessment of PC12 cell differentiation and neurite growth: a comparison of morphological and neurochemical measures
KP Das, TM Freudenrich, WR Mundy - Neurotoxicology and teratology, 2004 - Elsevier
… of the status of PC12 cell differentiation. … of PC12 cell differentiation. This work tested the
hypothesis that GAP-43 and synapsin I are sensitive to chemical disruption of differentiation and …
hypothesis that GAP-43 and synapsin I are sensitive to chemical disruption of differentiation and …
[HTML][HTML] Differential regulation of c‐Jun by ERK and JNK during PC12 cell differentiation
S Leppä, R Saffrich, W Ansorge, D Bohmann - The EMBO journal, 1998 - embopress.org
… To gain further insight into the relationship between ERK, JNK and c‐Jun activation in PC12
cell differentiation, we analysed the phosphorylation state and hence the activity of these …
cell differentiation, we analysed the phosphorylation state and hence the activity of these …
Mechanisms of manganese-induced rat pheochromocytoma (PC12) cell death and cell differentiation
JA Roth, C Horbinski, D Higgins, P Lein, MD Garrick - Neurotoxicology, 2002 - Elsevier
… PC12 cell differentiation requires the presence of an RGD-dependent interaction between
the cell … ERK1 and 2 were not seen in a PC12 cell line that does not respond to Mn-induced …
the cell … ERK1 and 2 were not seen in a PC12 cell line that does not respond to Mn-induced …
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Cell cycle‐specific action of nerve growth factor in PC12 cells: differentiation without proliferation.
BB Rudkin, P Lazarovici, BZ Levi, Y Abe, K Fujita… - The EMBO …, 1989 - embopress.org
… PC12 cells were manipulated in such a way as to permit the study of differentiation-specific …
These observations raised the possibility that PC 12 cells were responding to NGF in a cell …
These observations raised the possibility that PC 12 cells were responding to NGF in a cell …
PC12 cell line: cell types, coating of culture vessels, differentiation and other culture conditions
B Wiatrak, A Kubis-Kubiak, A Piwowar, E Barg - Cells, 2020 - mdpi.com
… or synthetic origin on neuronal cells. NGF-differentiated PC12 cells express the synapsin I
… has been proven to depend on the level of cell differentiation [11]. Synapsin I is involved in …
… has been proven to depend on the level of cell differentiation [11]. Synapsin I is involved in …
PC12 cells as a model of neuronal differentiation
G Guroff - Cell culture in the neurosciences, 1985 - Springer
… acetylcholine than were uptreated cells. Thus, generally speaking, NGF-treated PC12 cells
exhibited many of the properties of mature, terminally differentiated sympathetic neurons. …
exhibited many of the properties of mature, terminally differentiated sympathetic neurons. …
Regulation of the differentiation of PC12 pheochromocytoma cells.
K Fujita, P Lazarovici, G Guroff - Environmental health …, 1989 - ehp.niehs.nih.gov
… differentiation. When treated in culture with nanomolar concentrations of nerve growth factor,
PC12 cells stop … muscle cells in culture. The changes induced by nerve growth factor lead to …
PC12 cells stop … muscle cells in culture. The changes induced by nerve growth factor lead to …
Assay-based quantitative analysis of PC12 cell differentiation
T Ohuchi, S Maruoka, A Sakudo, T Arai - Journal of neuroscience methods, 2002 - Elsevier
… during PC12 cell differentiation, we developed cell enzyme-… is increased during PC12 cell
differentiation, we established … We found that the cell ELISA and cell counting assays could …
differentiation, we established … We found that the cell ELISA and cell counting assays could …
Induction of PC12 cell differentiation by flavonoids is dependent upon extracellular signal‐regulated kinase activation
Y Sagara, J Vanhnasy, P Maher - Journal of neurochemistry, 2004 - Wiley Online Library
… of flavonoids to induce nerve cell differentiation using PC12 cells. PC12 cells were treated
with a … In addition, the signaling pathways required for flavonoid-induced differentiation were …
with a … In addition, the signaling pathways required for flavonoid-induced differentiation were …