[HTML][HTML] A positive role of the PI3-K/Akt signaling pathway in PC12 cell differentiation
Y Kim, R Seger, SB CV, SY Hwang, YS Yoo - Molecules and cells, 2004 - Elsevier
… induces cell differentiation of PC12 cells as indicated by neurite outgrowth. In order to
investigate the role of PI3-K/Akt in NGF-induced differentiation of PC12 cells, we generated cells …
investigate the role of PI3-K/Akt in NGF-induced differentiation of PC12 cells, we generated cells …
Luteolin enhances cholinergic activities in PC12 cells through ERK1/2 and PI3K/Akt pathways
… AChE activity in PC12 cells in relation with ERK1/2 and Akt signaling. (A) Shows AChE-induced
activity of luteolin in PC12 cells after 24 h and 48 h treatment. PC12 cells were treated …
activity of luteolin in PC12 cells after 24 h and 48 h treatment. PC12 cells were treated …
[HTML][HTML] Neuroprotection of geniposide against hydrogen peroxide induced PC12 cells injury: involvement of PI3 kinase signal pathway
J Liu, F Yin, L Guo, X Deng, Y Hu - Acta Pharmacologica Sinica, 2009 - nature.com
… To explore the signal pathway by which geniposide prevents PC12 cells from oxidative
damage, we used LY294002 to investigate whether geniposide activates the PI3K pathway. It …
damage, we used LY294002 to investigate whether geniposide activates the PI3K pathway. It …
Resveratrol protects PC12 cells from high glucose-induced neurotoxicity via PI3K/Akt/FoxO3a pathway
MH Liu, C Yuan, J He, TP Tan, SJ Wu, HY Fu… - Cellular and molecular …, 2015 - Springer
… with the PI3K/Akt/FoxO3a in PC12 cells, we detected the effect of resveratrol on the expressions
of phosphorylated Akt and FoxO3a. The results showed that PC12 cell pretreatment with …
of phosphorylated Akt and FoxO3a. The results showed that PC12 cell pretreatment with …
PI3K/Akt signaling pathway ameliorates oxidative stress-induced apoptosis upon manganese exposure in PC12 cells
Y Tan, H Cheng, C Su, P Chen, X Yang - Biological Trace Element …, 2022 - Springer
… pretreatment also increased cell apoptosis given the upregulated Bax and Caspase-3
mRNAs and decreased Bcl-2 mRNA. In summary, the PI3K/Akt signaling pathway can be …
mRNAs and decreased Bcl-2 mRNA. In summary, the PI3K/Akt signaling pathway can be …
Erythropoietin protects PC12 cells from β-amyloid25–35-induced apoptosis via PI3K/Akt signaling pathway
R Ma, N Xiong, C Huang, Q Tang, B Hu, J Xiang… - Neuropharmacology, 2009 - Elsevier
… Our findings demonstrated that EPO can rescue PC12 cells from Aβ-induced apoptosis.
Furthermore, we found that activation of the PI3K pathway, via sustained phosphorylation of Akt, …
Furthermore, we found that activation of the PI3K pathway, via sustained phosphorylation of Akt, …
Icariin prevents amyloid beta‐induced apoptosis via the PI3K/Akt pathway in PC‐12 cells
D Zhang, Z Wang, C Sheng, W Peng… - Evidence‐Based …, 2015 - Wiley Online Library
… PI3K/Akt signaling through the phosphorylation of Akt (Ser473) [23], we evaluated Akt
phosphorylation in icariin-treated PC12 cells. … increased phosphorylation of Akt at Ser473, and that …
phosphorylation in icariin-treated PC12 cells. … increased phosphorylation of Akt at Ser473, and that …
N-acetylserotonin protects PC12 cells from hydrogen peroxide induced damage through ROS mediated PI3K/AKT pathway
J Kang, Y Wang, X Guo, X He, W Liu, H Chen, Z Wang… - Cell Cycle, 2022 - Taylor & Francis
… stimulated PC12 cells. In conclusion, NAS protected PC12 cells from apoptosis and oxidative
stress … by H 2 O 2 by inhibiting ROS activity and activating the PI3K/AKT signaling pathway. …
stress … by H 2 O 2 by inhibiting ROS activity and activating the PI3K/AKT signaling pathway. …
… Possesses Protective Potentials on H2O2‐Stimulated PC12 Cells by Suppression of Oxidative Stress‐Induced Apoptosis through Regulation of PI3K/Akt Signal Pathway
RL Li, Q Zhang, J Liu, J Sun, LY He… - … and Cellular …, 2020 - Wiley Online Library
… Cell Viability after the Inhibition of Signaling Pathway To further examine the role of the
PI3K/Akt signaling pathway in HAS protecting PC12 cells … of the PI3K/Akt signaling pathway by …
PI3K/Akt signaling pathway in HAS protecting PC12 cells … of the PI3K/Akt signaling pathway by …
Puerarin protects differentiated PC12 cells from H2O2‐induced apoptosis through the PI3K/Akt signalling pathway
Q Zhang, W Huang, X Lv, Y Yang - Cell Biology International, 2012 - Wiley Online Library
… To clarify the significance of the PI3K/Akt signal pathway in puerarin preventing PC12 cells
from apoptosis, differentiated PC12 cells were treated with puerarin and wortmannin for 2 h …
from apoptosis, differentiated PC12 cells were treated with puerarin and wortmannin for 2 h …
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