… induces cell differentiation of PC12 cells as indicated by neurite outgrowth. In order to
investigate the role of PI3-K/Akt in NGF-induced differentiation of PC12 cells, we generated cells …

… AChE activity in PC12 cells in relation with ERK1/2 and Akt signaling. (A) Shows AChE-induced
activity of luteolin in PC12 cells after 24 h and 48 h treatment. PC12 cells were treated …

… To explore the signal pathway by which geniposide prevents PC12 cells from oxidative
damage, we used LY294002 to investigate whether geniposide activates the PI3K pathway. It …

… with the PI3K/Akt/FoxO3a in PC12 cells, we detected the effect of resveratrol on the expressions
of phosphorylated Akt and FoxO3a. The results showed that PC12 cell pretreatment with …

… pretreatment also increased cell apoptosis given the upregulated Bax and Caspase-3
mRNAs and decreased Bcl-2 mRNA. In summary, the PI3K/Akt signaling pathway can be …

… Our findings demonstrated that EPO can rescue PC12 cells from Aβ-induced apoptosis.
Furthermore, we found that activation of the PI3K pathway, via sustained phosphorylation of Akt, …

… PI3K/Akt signaling through the phosphorylation of Akt (Ser473) [23], we evaluated Akt
phosphorylation in icariin-treated PC12 cells. … increased phosphorylation of Akt at Ser473, and that …

… stimulated PC12 cells. In conclusion, NAS protected PC12 cells from apoptosis and oxidative
stress … by H 2 O 2 by inhibiting ROS activity and activating the PI3K/AKT signaling pathway. …

… Cell Viability after the Inhibition of Signaling Pathway To further examine the role of the
PI3K/Akt signaling pathway in HAS protecting PC12 cells … of the PI3K/Akt signaling pathway by …

… To clarify the significance of the PI3K/Akt signal pathway in puerarin preventing PC12 cells
from apoptosis, differentiated PC12 cells were treated with puerarin and wortmannin for 2 h …