Insulin-like growth factor-1 induces the phosphorylation of PRAS40 via the PI3K/Akt signaling pathway in PC12 cells
… by IGF-1 in PC12 cells and explored the signaling pathway responsible for the effect of
IGF-1… of Akt at Thr473 and PRAS40 at Thr246 in PC12 cells. The phosphorylation of Akt and …
IGF-1… of Akt at Thr473 and PRAS40 at Thr246 in PC12 cells. The phosphorylation of Akt and …
Tanshinone IIA protects PC12 cells from β-amyloid25–35-induced apoptosis via PI3K/Akt signaling pathway
… of PC12 cells, we induced apoptosis in PC12 cells with β-amyloid 25–35 , and treated cells
… Tan IIA increased the cell viability and reduced the number of apoptotic cells induced by Aβ …
… Tan IIA increased the cell viability and reduced the number of apoptotic cells induced by Aβ …
Deprenyl prevents MPP+-induced oxidative damage in PC12 cells by the upregulation of Nrf2-mediated NQO1 expression through the activation of PI3K/Akt and Erk
H Xiao, F Lv, W Xu, L Zhang, P Jing, X Cao - Toxicology, 2011 - Elsevier
… in PC12 cells is independent of MAO-B inhibition. Altogether, our findings indicate that deprenyl
protects PC12 cells … upregulation of NQO1 involving both the PI3K/Akt and Erk pathways. …
protects PC12 cells … upregulation of NQO1 involving both the PI3K/Akt and Erk pathways. …
… growth factor differentiated PC12 cells from oxidative-radical-stress-induced apoptosis through its effect on phosphoinositide 3-kinase/Akt and glycogen synthase …
… PI3K/Akt, GSK-3 pathway in a neuronal cell line have not previously been investigated. This
study demonstrates that EGCG protects PC12 cells … through the PI3K/Akt, GSK-3 pathway, as …
study demonstrates that EGCG protects PC12 cells … through the PI3K/Akt, GSK-3 pathway, as …
Hypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells: protective role in apoptosis
M Alvarez-Tejado, S Naranjo-Suárez, C Jiménez… - Journal of Biological …, 2001 - ASBMB
… results in the activation of the PI3K/Akt pathway in PC12 cells by a novel mechanism that
involvesde novo protein synthesis. The activation of this pathway by hypoxia results in the …
involvesde novo protein synthesis. The activation of this pathway by hypoxia results in the …
… marrow mesenchymal stem cell-derived microvesicles protect rat pheochromocytoma PC12 cells from glutamate-induced injury via a PI3K/Akt dependent pathway
SS Lin, B Zhu, ZK Guo, GZ Huang, Z Wang… - Neurochemical …, 2014 - Springer
… Our study demonstrated that MVs induced Akt phosphorylation in PC12 cells in a dose- and
… -induced downregulation of Akt phosphorylation and Bcl-2 expression in PC12 cells, and the …
… -induced downregulation of Akt phosphorylation and Bcl-2 expression in PC12 cells, and the …
[HTML][HTML] Tenuifoliside A promotes neurite outgrowth in PC12 cells via the PI3K/AKT and MEK/ERK/CREB signaling pathways
X Liu, X Wang, J Lu - Molecular Medicine Reports, 2015 - spandidos-publications.com
… with the PD98059 MEK inhibitor and LY294002 PI3K inhibitor inhibited the neurite outgrowth
… of PC12 cells and suggested that activation of the MEK/ERK/CREB and PI3K/Akt signaling …
… of PC12 cells and suggested that activation of the MEK/ERK/CREB and PI3K/Akt signaling …
… oxygen and glucose deprivation/reperfusion-induced PC12 cell injury through inhibition of apoptosis and autophagy by activating the PI3K/AKT/mTOR pathway
J Meng, H Ma, Y Zhu, Q Zhao - European Journal of Pharmacology, 2021 - Elsevier
… /R-induced neuronal injury in PC12 cells. In this study, PC12 cells were subjected to OGD
… autophagy following OGD/R in PC12 cells. Results may provide pharmacological evidence …
… autophagy following OGD/R in PC12 cells. Results may provide pharmacological evidence …
Panaxatriol saponins attenuated oxygen‐glucose deprivation injury in PC12 cells via activation of PI3K/Akt and Nrf2 signaling pathway
Y Huang, J Yu, F Wan, W Zhang, H Yang… - … and cellular …, 2014 - Wiley Online Library
… of PTS on the activation of Nrf2 signaling pathway and the potential role in its protective …
in PC12 cells via activating Nrf2 signaling pathway. Phosphatidylinositol 3-kinase (PI3K)/Akt …
in PC12 cells via activating Nrf2 signaling pathway. Phosphatidylinositol 3-kinase (PI3K)/Akt …
Tanshinone IIA attenuates insulin like growth factor 1-induced cell proliferation in PC12 cells through the PI3K/Akt and MEK/ERK pathways
… -proliferative effect of TSN in PC12 cells and its role on … cell viability of PC12 cells in the
presence of IGF-1, we then wanted to know whether TSN would affect the apoptosis of PC12 cells…
presence of IGF-1, we then wanted to know whether TSN would affect the apoptosis of PC12 cells…