… cell viability of H 2 O 2 -stimulated PC12 cells and reduced apoptotic cells and ROS levels in
H 2 O 2 -stimulated PC12 cells… PC12 cells. Moreover, BBPs upregulated the expressions of …

… via the PI3K pathway, … PC12 cells apoptosis through activation of the Akt/GSK-3β/caspase-3
mediated signaling mechanism. Treatment of recombinant EPO in PC12 cells activates Akt, …

… cell type and injury (Komandirov et al., 2011). Inhibition of AKT and mTOR reduces acute cell
… expression levels of related proteins in this pathway in PC12 cells, and to explore the role …

… Our results elucidate that silencing PAQR3 can protect PC12 from OGD/R injury via activating
PI3K/AKT pathway. And therefore, provide a novel therapeutic target for the prevention of …

… PC12 cells compared with PC12 cells without Aβ 1–42 . Both results were consistent.
After resveratrol application, the expression of HO-1 was increased in a concentration-dependent …

… to protect PC12 cells from corticosterone toxicity by regulating PI3K/Akt/FoxO3a pathway. …
and FoxO3a stimulated by venlafaxine is mediated by the PI3K pathway as the PI3K inhibitor; …

… Akt/mTOR activity simultaneously. To this end PC12 cells as commonly used neural like cells
… transcriptional and post-translational levels of PI3K/Akt/mTOR/S6K signaling components. …

… To explore potential intracellular signaling mechanisms responsible for the protective effects
of linarin against Aβ 25–35 -induced PC12 cell death, we assessed for changes in PI3K/Akt …

… We also found that the number of apoptotic cells in the PC12 cells significantly increases
after Aβ 25–35 treatment, which suggests the role of apoptosis in the development of Aβ-…

… 3-kinase (PI3K) inhibitors LY294002 and Wortmannin. … pathway suppresses 6-OHDAinduced
PC12 cell apoptosis by suppressing the mitochondrial apoptosis signal via PKG/PI3K/Akt…