[HTML][HTML] Protodioscin protects PC12 cells against oxygen and glucose deprivation-induced injury through miR-124/AKT/Nrf2 pathway

K Shu, Y Zhang - Cell Stress and Chaperones, 2019 - Elsevier
… in PC12 cells, which was also effectively reversed by Prot treatment. Prot protected PC12 cells
… HSP proteins expression via activating PI3K/AKT/Nrf2 pathway and miR-124 modulation. …

Luteolin-induced protection of H2O2-induced apoptosis in PC12 cells and the associated pathway

P Lin, XH Tian, YS Yi, WS Jiang… - Molecular …, 2015 - spandidos-publications.com
… mediated through the PI3K/Akt pathway, PC12 cells were pretreated with LY294002, a
PI3K/Akt inhibitor. The results demonstrated that the effects of luteolin on p-Akt levels (Fig. 5A), …

Akt phosphorylation is essential for nuclear translocation and retention in NGF-stimulated PC12 cells

TLX Nguyen, JW Choi, SB Lee, K Ye, SD Woo… - Biochemical and …, 2006 - Elsevier
PI3K activity is indeed required for the maintenance of Akt … of cells stimulated with NGF, we
infected PC12 cells with an … -negative PI3K, followed by the treatment of these cells with or …

The atypical antipsychotic agent, clozapine, protects against corticosterone-induced death of PC12 cells by regulating the Akt/FoxO3a signaling pathway

Z Zeng, X Wang, SK Bhardwaj, X Zhou, PJ Little… - Molecular …, 2017 - Springer
… effect of clozapine on the PC12 cells against corticosterone toxicity. Our … PC12 cells
against corticosterone-induced cell death by modulating activity of the PI3K/Akt/FoxO3a pathway

… -1) induces the activation/phosphorylation of Akt kinase and cAMP response element-binding protein (CREB) by activating different signaling pathways in PC12 cells

WH Zheng, R Quirion - BMC neuroscience, 2006 - Springer
… multiple signaling pathways but in particular the PI3K/Akt kinase and MAPK-CREB pathways
[2, 30, … the activation of both the PI3K/Akt kinase and MAPK-CREB pathways in PC12 cells. …

NGF-induced moesin phosphorylation is mediated by the PI3K, Rac1 and Akt and required for neurite formation in PC12 cells

S Jeon, JK Park, CD Bae, J Park - Neurochemistry international, 2010 - Elsevier
… of cells with neurites following NGF treatment. Our results indicate that PI3K, Rac1 and
Akt-… of moesin is required for the NGF-induced neurite formation in differentiating PC12 cells. …

… Effects of Deuterium-Depleted Water (DDW) Against H2O2-Induced Oxidative Stress in Differentiated PC12 Cells Through the PI3K/Akt Signaling Pathway

Y Wu, D Qin, H Yang, W Wang, J Xiao, L Zhou… - Neurochemical …, 2020 - Springer
… the phosphatidylinositol-3-kinase (PI3K) inhibitor LY294002. In summary, DDW may protect
PC12 cells against H 2 O 2 -induced oxidative stress through the PI3K/Akt signaling pathway

[HTML][HTML] MiR-130a exerts neuroprotective effects against ischemic stroke through PTEN/PI3K/AKT pathway

T Zheng, Y Shi, J Zhang, J Peng, X Zhang… - Biomedicine & …, 2019 - Elsevier
… Our findings indicated that miR-130a expression was lower in PC12 cells after OGDR (oxygen-glucose
deprivation/reperfusion) and in rats after MCAO (middle cerebral artery occlusion)…

… -induced oxidative damage via upregulation of phosphatidylinositol-3-kinase/Akt and modulation of extracellular signal-regulated kinase 1/2 activation in PC12 cells …

L Liu, JX Cao, B Sun, HL Li, Y Xia, Z Wu, CL Tang, J Hu - Neuroscience, 2010 - Elsevier
PI3K)/Akt and a lasting activation of extracellular signal-regulated kinase 1/2 (ERK1/2) in …
PC12 cells and primary cortical neurons which were able to be reversed by MSC-CM. The PI3K

Second-generation antipsychotic drugs, olanzapine, quetiapine, and clozapine enhance neurite outgrowth in PC12 cells via P13K/AKT, ERK, and pertussis toxin …

XH Lu, DS Dwyer - Journal of Molecular Neuroscience, 2005 - Springer
cell differentiation in PC12 cells in relation to PI3K/Akt and ERK signal transduction pathways.
The PC12 cell … has been widely used as a cell model to study differentiation and signal …