The role of the PD-L1: PD-1 pathway in squamous cell carcinoma of the head and neck

DP Zandberg, SE Strome - Oral oncology, 2014 - Elsevier
… of PD-L1:PD-1 blockade for the treatment of recurrent/metastatic squamous cell carcinoma
… In this review we will explore what is known about the interactions between PD-1 and PD-L1

[HTML][HTML] Intrinsic and extrinsic control of expression of the immunoregulatory molecule PD-L1 in epithelial cells and squamous cell carcinoma

P Ritprajak, M Azuma - Oral oncology, 2015 - Elsevier
… and malignant cells with a particular focus on epithelial cells and squamous cell
carcinoma (SCC), and we discuss intrinsic and extrinsic regulation of PD-L1 expression. …

Prognostic role of PD-L1 expression in renal cell carcinoma. A systematic review and meta-analysis

R Iacovelli, F Nolè, E Verri, G Renne, C Paglino… - Targeted …, 2016 - Springer
… the prognostic role of PD-L1 in clear cell carcinoma, while one only included patients with
non-clear cell histology. Five studies used the IHC assay to evaluate PD-L1 expression (1141 …

[HTML][HTML] PD-L1 expression in nonclear-cell renal cell carcinoma

TK Choueiri, AP Fay, KP Gray, M Callea, TH Ho… - Annals of oncology, 2014 - Elsevier
… /5 (20%) of collecting duct carcinoma. PD-L1 positivity (PD-L1+) in tumor cells was significantly
… On the other hand, PD-L1 positivity by TIMC was observed in 57 (56.4%) patients: 13/36 (…

[HTML][HTML] Basal cell carcinoma: PD-L1/PD-1 checkpoint expression and tumor regression after PD-1 blockade

EJ Lipson, MT Lilo, A Ogurtsova, J Esandrio… - … for immunotherapy of …, 2017 - Springer
… (anti-PD-1) in a patient with metastatic PD-L1 (+) basal cell carcinoma, whose disease had
… for testing anti-PD-1 therapy in patients with advanced basal cell carcinoma, either as initial …

PD-1 and PD-L1 expression in renal cell carcinoma with sarcomatoid differentiation

RW Joseph, SZ Millis, EM Carballido, D Bryant… - Cancer immunology …, 2015 - AACR
… 1 (PD-1)–programmed death ligand-1 (PD-L1) axis have antitumor activity against multiple
cancers. The presence of sarcomatoid differentiation in renal cell carcinoma (… the PD-1/PD-L1

PD-L1 expression is a favorable prognostic factor in early stage non-small cell carcinoma

WA Cooper, T Tran, RE Vilain, J Madore, CI Selinger… - Lung cancer, 2015 - Elsevier
… 1 (PD-L1) tumoral expression could potentially be a useful predictive marker. Data reporting
the prevalence of PD-L1 … We sought to determine the frequency of PD-L1 expression in …

Evidence for a role of the PD-1: PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma

S Lyford-Pike, S Peng, GD Young, JM Taube… - Cancer research, 2013 - AACR
… studies with anti-PD-1(BMS-936558) and anti-PD-L1 (BMS-… renal cell carcinoma, melanoma,
and non–small cell lung cancer, and again a relationship between tumor cell surface PD-L1

[HTML][HTML] CD274/PD-L1 gene amplification and PD-L1 protein expression are common events in squamous cell carcinoma of the oral cavity

M Straub, E Drecoll, N Pfarr, W Weichert, R Langer… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… In the present study, expression of PD-L1 and PD-1 was evaluated by … -negative oral
squamous cell carcinomas and associated nodal metastasis. In addition, CD274/PD-L1 gene copy …

Differential expression of PD-L1 between primary and metastatic sites in clear-cell renal cell carcinoma

M Callea, L Albiges, M Gupta, SC Cheng… - Cancer immunology …, 2015 - AACR
PD-L1 expression in primary clear-cell renal cell carcinoma (ccRCC) increases the likelihood
of response to anti–PD… We hypothesized that PD-L1 levels assessed in randomly selected …