PD-L1

A Kythreotou, A Siddique, FA Mauri, M Bower… - Journal of clinical …, 2018 - jcp.bmj.com
… In this review, we discuss the immunobiology of PD-L1, with a particular focus on its …
PD-1/PD-L1.23 HIV-specific CD4/CD8 cells coexpress PD-1, and a similar role for PD-1/PD-L1 has …

PD-L1 expression in cancer patients receiving anti PD-1/PD-L1 antibodies: A systematic review and meta-analysis

S Gandini, D Massi, M Mandalà - Critical reviews in oncology/hematology, 2016 - Elsevier
… -PD-1 therapies for three tumor histotypes: MM, NSCLC and RCC. All of them are the focus
of the present systematic review … receiving anti-PD-1/PD-L1 therapy has been reviewed and …

Comparison of biomarker modalities for predicting response to PD-1/PD-L1 checkpoint blockade: a systematic review and meta-analysis

S Lu, JE Stein, DL Rimm, DW Wang, JM Bell… - JAMA …, 2019 - jamanetwork.com
… Findings In this systematic review and meta-analysis involving … than PD-L1 IHC, tumor
mutational burden, or gene expression profiling in predicting clinical response to anti–PD-1/PD-L1

[HTML][HTML] PD-1/PD-L1 pathway: current researches in cancer

Y Han, D Liu, L Li - American journal of cancer research, 2020 - ncbi.nlm.nih.gov
… Based on these perspectives, PD-1/PD-L1 axis is responsible … review is aimed to summarize
the role of PD-1 and PD-L1 in … of the present review was to elucidate the role of PD-1/PD-L1

[HTML][HTML] PD-L1 and gastric cancer prognosis: A systematic review and meta-analysis

L Gu, M Chen, D Guo, H Zhu, W Zhang, J Pan… - PloS one, 2017 - journals.plos.org
review focuses on PD-L1 expression and its association with clinical outcomes in GC.
Furthermore, this research attempts to show that the potential of PD-L1 … inhibition of PD-L1/PD-1 …

Progress and challenges of predictive biomarkers of anti PD-1/PD-L1 immunotherapy: a systematic review

F Teng, X Meng, L Kong, J Yu - Cancer letters, 2018 - Elsevier
… Despite the marked success of applications of PD-1/PD-L1 checkpoint … In this review, we
discuss the current progress and … PD-L1 expression is a logical biomarker for the prediction of …

[HTML][HTML] Mechanisms controlling PD-L1 expression in cancer

JH Cha, LC Chan, CW Li, JL Hsu, MC Hung - Molecular cell, 2019 - cell.com
… Therefore, furthering our understanding of the regulatory mechanisms of PD-L1 can bring …
PD-L1/PD-1 blockade or other ICBs. In this review, we provide current knowledge of PD-L1

[HTML][HTML] PD-L1 diagnostic tests: a systematic literature review of scoring algorithms and test-validation metrics

M Udall, M Rizzo, J Kenny, J Doherty, SA Dahm… - Diagnostic …, 2018 - Springer
PD-L1 IHC assays, we systematicallyPD-L1 IHC tests in lung cancer, most using
immunohistochemistry testing. There was significant heterogeneity among the available tests for …

[HTML][HTML] Combination strategies with PD-1/PD-L1 blockade: current advances and future directions

M Yi, X Zheng, M Niu, S Zhu, H Ge, K Wu - Molecular cancer, 2022 - Springer
review, we summarized the synergistic antitumor efficacies and mechanisms of α-PD-1/PD-L1
Moreover, we focused on the advances of α-PD-1/PD-L1-based immunomodulatory …

[HTML][HTML] Biomarkers for predicting efficacy of PD-1/PD-L1 inhibitors

M Yi, D Jiao, H Xu, Q Liu, W Zhao, X Han, K Wu - Molecular cancer, 2018 - Springer
… (PD-1/PD-L1) is a negative modulatory signaling pathway for activation of T cell. It is
acknowledged that PD-1/PD-L1 … immune therapy strategies, PD-1/PD-L1 inhibitor is a …